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Videos
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February 22, 2024
EVOM™ Auto, with both 24 and 96 HTS multiwell plate capability, is a high throughput screening (HTS) platform offering fast, noninvasive sample scanning by comparing electrical resistance measurements (transepithelial/transendothelial electrical resistance: TEER). TEER measurement experiments are simple to set up and less time consuming than more complex molecular studies. TEER measurement can be used as the primary scanning method to identify any physiological changes that can then be further evaluated by other methods. EVOM™ Auto can capture TEER measurements in 24 and 96 HTS multiwell plates from Corning, Millipore, or MatTek. The sample preparation time in these HTS plates is efficient, allowing for fast, multi-channel pipetting options.
The EVOM™ Auto autosampler ships with a red electrode array lock in place to prevent the electrode array connection port from moving during transit. Here you can see how to easily remove it without damaging the lock or the autosampler...more
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February 16, 2024
The WPSS01 skin stapler is an affordable, reliable solution for veterinary wound closures. A skin stapler is designed for the efficient closure of surgical incisions or wounds by applying surgical staples to the skin, reducing surgery time and time under anesthesia. Each disposable skin staple cassette contains at least thirty-five (35) 316L stainless steel staples.
Each reusable skin stapler handle is provided sterile with one disposable staple cassette already loaded into the handle. Discard the disposable staple cassette after the procedure. The reusable handle may be cleaned and resterilized (autoclave, EO) for subsequent procedures and will effectively deploy at least twenty (20) disposable staple cassettes and withstand at least twenty (20) autoclave cycles...more
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November 13, 2023
Let’s take a look at how to set up a Digital Rat/Mouse, Neonatal Rat Stereotaxic frame. In a few steps you will be up and running...more
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July 24, 2023
In 2022, the United States Food and Drug Administration (FDA) approved 37 new drugs, of which 20 were chemical entities and 17 were biologics. In 2023, drug discovery remains strong with many new advancements a result of changing landscapes in both the types of drugs that are being developed and the new and innovative assay that are being launched to evaluate drugs preclinically. Therapeutic development is still highly focused on diseases that affect large populations of people for which there are lack of effective treatments, with 2023’s most anticipated drug launches expected to be in areas of cancer, Alzheimer’s disease, cardiovascular disease, and ulcerative colitis...more
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July 19, 2023
In 2022, the United States Food and Drug Administration (FDA) approved 37 new drugs, of which 20 were chemical entities and 17 were biologics. In 2023, drug discovery remains strong with many new advancements a result of changing landscapes in both the types of drugs that are being developed and the new and innovative assay that are being launched to evaluate drugs preclinically. Therapeutic development is still highly focused on diseases that affect large populations of people for which there are lack of effective treatments, with 2023’s most anticipated drug launches expected to be in areas of cancer, Alzheimer’s disease, cardiovascular disease, and ulcerative colitis...more
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May 25, 2023
If the EVOM™ Auto software switches from Resistance to TEER mode while you are selecting menu options, here's a quick tip:
Be careful when selecting Resistance mode, do not tap the background window and do not click on the side arrows.
Tapping the background window will switch you to TEER mode.
Instead, tap an option on the forefront square window to stay in Resistance mode...more
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May 02, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows details the features and functions of the Experiment window on the EVOM™ Auto:
After you have defined a sequence, you can begin running an experiment.
The Experiment window shows a representation of the plate on the left side of the window.
On the right side of the window, you see these...more
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April 27, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to schedule an operation on the EVOM™ Auto:
The data acquisition functions of the EVOM™ Auto may be repeated at a defined time interval when multiple scans of a plate are needed. The scheduled operations are displayed on the right side of the Experiment window in the Current State area. The control buttons for scheduling...more
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April 25, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to stabilize the electrode array on the EVOM™ Auto:
First, select Maintenance on the main menu. To stabilize, press the + or - buttons to set the timer to the desired time in minutes in the stablize frame.
Next, Select the radio button for the rinse station containing the buffer solution. Then, fill the appropriate rinse station with the buffer solution...more
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April 20, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to chloride the electrode array on the EVOM™ Auto:
To chloride the electrode array, select Maintenance on the main menu.
Four control buttons are located at the bottom of this window:
- Go Home- Positions the electrode array in the home position.
- Calibrate- Calibrates the sensor head using the internal...more
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April 18, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to create a plate file on the EVOM™ Auto:
1. To Create a measurement sequence, select the Manage Sequence menu from the Home screen. A list of the existing sequences displays, and you may open and edit any existing sequence or select New Sequence to create a new one. If you select New Sequence, a popup allows you to...more
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April 13, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to download and how to delete a data file EVOM™ Auto:
Once a data acquisition run is complete, the data may be exported. This process exports all the runs performed on a plate into a downloadable, comma-delimited (CSV) file which can be read by Microsoft® Excel or Google Sheets. The downloaded file is immediately available.
To download a data file, press the Download...more
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April 11, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to run an experiment on the EVOM™ Auto:
To begin running an experiment, select Experiment from the main menu. Then, select the Plate Name drop-down in the Details area on the right side of the screen. Choose from the list of existing plates or select New Plate to define a new plate. Enter the name for the plate...more
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April 06, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you the features of the homepage on the EVOM™ Auto:
Introducing the Home Screen – Tips for Getting Started
Select a Plate Brand
The Electrode Array is configured to support 96-well plates. Three different brands of plates are supported:- C96_HTC – Corning 96 Well Plate
- M96_HTC – Milipore 96 Well Plate
- O96_HTC...more
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March 31, 2023
On the new WPI website, multiple related products may be grouped together to make them easier to compare.
The price range of all the options is shown at the top left corner of the product page.
To make a selection easier, a grid in the Details area (below the images) lists the details of all the products listed on the page, including the order code.
Click Choose an Option to select the model you want. If the option price deviates from the default selection, you see the additional cost listed next to the option. In this example in the video, the curved scissors cost $4 more than the straight, and the German steel scissors cost $43 more.
When you select your option, the price of your selection shows at the top of the screen.
Select the quantity you need and click the Add to Cart button. The shopping cart reflects the price of your option.
If you have any...more