WPI's PermaCell 96-well insert plates are advanced, sterile cell culture devices used for growth and differentiation of cells. The plates consist of an array of 96 membrane wells connected in a single, rigid tray for easier handling and feeding and to allow for high-throughput robotic processing. These MatTek 96-well insert plate fits within a 96-well receiver plate (included) which allows for individual treatment and assaying of each well in the plate. PermaCell insert plates can be used for cell culture and cell differentiation into 2D/3D tissues, drug transport/permeability studies, and imaging studies.