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Blog
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February 25, 2021
NanoFil™ is a unique low volume syringe developed for improved microinjection in mice and other small animals. NanoFil needles are specially designed with a small outside diameter and spear point for shallow penetration and to cause the least amount of tissue damage.
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February 25, 2021
NanoFil™ is a unique low volume syringe developed for improved microinjection in mice and other small animals. During our field trials, the 35-gauge needle was scientists’ most popular and preferred NanoFil tip. The combination of its strength, length, durability and clogging resistance creates a solid balance.
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February 25, 2021
NanoFil™ is a unique low volume syringe developed for improved microinjection in mice and other small animals. Here we'll show you how to install your needle in a way that prevents damage to the gasket and keeps your needles straight.
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February 25, 2021
NanoFil™ is a unique low volume syringe developed for improved microinjection in mice and other small animals. Using a UMP3 UltraMicroPump combined with the syringe allows you to make repeatable injections in the nanoliter range. Here we'll show you how to install a NanoFil Syringe on the UMP3 UltraMicroPump.
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February 22, 2021
Pulling micropipettes or microelectrodes is a science and an art, requiring some finesse. Here we discuss the five major factors which can affect the shape of a pulled glass micropipette or microelectrode.
The PUL-1000 is a microprocessor controlled, four-stage, horizontal puller for making glass micropipettes or microelectrodes. Here we will look at factors that affect the pulling of glass.
As the temperature of glass increases, the glass transitions gradually from a hard and relatively brittle solid state into a soft and viscous state. To form glass into certain shapes using a puller, heat is applied through a filament. Many factors affect the heat transferred from a filament to a glass capillary.
- The filament holders heat up when current passes through the filament, which can...more
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February 22, 2021
DCAP guillotines are designed for small animal researchers, and they come in three sizes. The DCAP is considered one of the most humane methods of dispatching laboratory animals. With a single downward motion of the handle, you can euthanize a laboratory rodent quickly and without trauma.
These guillotines are designed for small animal researchers, and they come in three sizes. The guillotine is considered one of the most humane methods of dispatching laboratory animals. With a single downward motion of the handle, you can euthanize a rodent quickly and without trauma.
The blades are comprised of hardened steel, so they hold an edge and remain sharp, offering years of service. Sharp blades make the process swift for both the researcher and the subject. With proper care, the stainless steel blades...more
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February 12, 2021
Manual micromanipulators are common equipment in a laboratory, and with proper care and handling they should last many years. Here's a few tips on how to take care of your new manipulator.
Your micro manipulator is a precision instrument, and it has been calibrated at the factory and is ready to use. As with any delicate mechanical device, your care and attention ensure long-term accurate performance. The following are some helpful hints that make this possible.
- When handling a micromanipulator like the M3301 or the KITE, always set it down carefully. Dropping it even a short distance can damage the general alignment and the adjustment.
- When it's not in use, close all the slides. When the guides are exposed, dust can get in those tracks. When...more
- When handling a micromanipulator like the M3301 or the KITE, always set it down carefully. Dropping it even a short distance can damage the general alignment and the adjustment.
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February 12, 2021
The M3301 is a popular micromanipulator used for laboratory research. Here we will show you how to mount a microelectrode holder on the M3301 Micromanipulator. The procedure is very similar for most manual micromanipulators.
In this video, we use the popular M3301 Micromanipulator to demonstrate how to mount a standard electrode holder. This M3301 is mounted on an M-3 Tilt Base which allows you to position it the way you want. The Tilt Base is mounted on a 5-lb. Weighted Base (WPI #...more
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February 12, 2021
Over time, you may experience mechanical drift in one or more of the axes of your manual micromanipulator. Here we show you how to adjust for that. The process is similar for other styles of manual micromanipulators. We will look at the process for adjusting all three axes of a KITE micromanipulator.
A micromanipulator axis may begin to move gradually under its own weight even if it's not being touched. This phenomenon is referred to as mechanical drift, and it occurs from normal use of the manipulator axes over time. Each coarse axis control of the micromanipulator has its own separate adjustment to counteract drift. Let's look at the popular M3301 Micromanipulator. The procedure...more
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February 11, 2021
M3301 is a popular manual micromanipulator at WPI. These manipulators are typically mounted on a stand or table to ensure stability. In this video we show you how to mount the manipulator on an Tilt Base (WPI# M-3) with a WPI# 5464 5 lb. weighted base.
When we mount a micromanipulator on an M-3 tilt base, the tilt base can be adjusted to position the micromanipulator right where you want it. We will use our popular M3301 micromanipulator to demonstrate.
- The first thing we need to do is remove the ring clamp from the bottom of the micromanipulator. There are two screws that we...more