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Micromanipulators

  1. How to Read a Vernier Scale
    April 08, 2021
    Vernier scales can be used on microscopes, stereotaxic frames and micromanipulators. The vernier scale was invented by French mathematician Pierre Vernier in 1631 as an upgrade on Pedro Nunes' measurement system for precision astrolobes. With a main scale and a sliding secondary scale, a vernier is used for making precise measurements.    How a Vernier Scale Works The vernier scale is marked with divisions slightly smaller than the divisions of the main scale. For example, a vernier scale could have 11 markings for every 10 on the main scale. That's 10 divisions on the vernier scale for every 9 on the main scale. This means that the vernier divisions are each 90% of the main scale divisions. In this case, the 0-line and the 10-line on the vernier could pair up with marks on the main scale, but none of the other divisions on the vernier would match a line of the main scale. For example, the 0 and 10-lines of the vernier scale could pair up with the 0 and 9-lines on the main scale. If the 0-line pairs up with a mark, the first division of the vernier (1 mark) would be 10% short of reaching a mark of the main scale, the second division (2 mark) would miss a mark on the main scale by 20%, the third division (3 mark) would miss a mark on the main scale by 30%, etc.   How to Read a Linear Vernier Scale Follow these steps to read the vernier scale: Read the main scale. Look for the last whole increment visible before the 0 (zero) mark. Read the secondary scale (Vernier) measurement. This is the division tick mark that lines up best with a mark on the main scale. Add the two measurements together. The image at the right shows a linear scale. The 0 on the vernier scale lines up with the 4 on the main scale. Notice that the 10 on the vernier scale also lines up with a mark on the main scale (4.9). We ignore the second mark that lines up. So, the measurement shown is 4.00mm. The second
  2. How to Adjust for Mechanical Drift in an M3301 Manual Micromanipulator
    February 12, 2021
    Over time, you may experience mechanical drift in one or more of the axes of your manual micromanipulator. Here we show you how to adjust for that. The process is similar for other styles of manual micromanipulators. We will look at the process for adjusting all three axes of a KITE micromanipulator.     A micromanipulator axis may begin to move gradually under its own weight even if it's not being touched. This phenomenon is referred to as mechanical drift, and it occurs from normal use of the manipulator axes over time. Each coarse axis control of the micromanipulator has its own separate adjustment to counteract drift. Let's look at the popular M3301 Micromanipulator. The
  3. How to Mount an Electrode Holder on Your Micromanipulator
    February 12, 2021
    The M3301 is a popular micromanipulator used for laboratory research. Here we will show you how to mount a microelectrode holder on the M3301 Micromanipulator. The procedure is very similar for most manual micromanipulators. In this video, we use the popular M3301 Micromanipulator to demonstrate how to mount a standard electrode holder. This M3301 is mounted on an M-3 Tilt Base which allows you to position it the way you want. The Tilt Base is mounted on a 5-lb. Weighted Base (WPI #
  4. How to Extend the Life of Your Micromanipulator
    February 12, 2021
    Manual micromanipulators are common equipment in a laboratory, and with proper care and handling they should last many years. Here's a few tips on how to take care of your new manipulator. Your micro manipulator is a precision instrument, and it has been calibrated at the factory and is ready to use. As with any delicate mechanical device, your care and attention ensure long-term accurate performance. The following are some helpful hints that make this possible. When handling a micromanipulator like the M3301 or the KITE, always set it down carefully. Dropping it even a short distance can damage the general alignment and the adjustment. When it's not in use, close all the slides. When the guides are exposed, dust can get in those tracks. When you're not using you manipulator, you want to close those up so the guide track are completely covered. Always cover the micromanipulator with a plastic bag or some kind of covering to keep the dust off. Dust particles and dirt are your biggest enemies. They get in the tracks and clogs the mechanisms. If the manipulator is not in use for a long period of time, be sure to occasionally work the slides to keep the grease pliable. Work them back and forth to keep them keep the grease pliable. Don't ever oil the guide surfaces. Under normal use, you shouldn't even need to apply grease for many years. If you have any questions, give us a call at (866) 606-1974 (Toll free in the USA) or email us at wpi@wpiinc.com.       See All Manual Manipulators  
  5. How to Mount an M3301 Micromanipulator on a Tilt Base
    February 11, 2021
    M3301 is a popular manual micromanipulator at WPI. These manipulators are typically mounted on a stand or table to ensure stability. In this video we show you how to mount the manipulator on an Tilt Base (WPI# M-3) with a WPI# 5464 5 lb. weighted base. When we mount a micromanipulator on an M-3 tilt base, the tilt base can be adjusted to position the micromanipulator right where you want it. We will use our popular M3301 micromanipulator to demonstrate. The first thing we need to do is remove the ring clamp from the bottom of the micromanipulator. There are two screws that
  6. How to Adjust for Mechanical Drift in a KITE Manual Micromanipulator
    February 10, 2021
    Over time, you may experience mechanical drift in one or more of the axes of your manual micromanipulator. Here we show you how to adjust for that. The process is similar for other styles of manual micromanipulators. We will look at the process for adjusting all three axes of a KITE micromanipulator.   Let's talk about mechanical drift on a micromanipulator and how to correct it. In this demonstration, we will use the popular KITE. A manipulator axis may begin to move gradually under its own weight, even if it's not being touched. This is called mechanical drift, and it happens from normal use of the manipulator over time. Each course axis control on the micromanipulator has its own adjustments. This procedure is very similar to the one we used for adjusting an M3301 micromanipulator. It also
  7. Magnetic Stands for Micromanipulators Give You an Extra Hand
    February 09, 2021
    Magnetic stands act as an invaluable extra hand around the laboratory to hold an electrode, digital dials or tools. The base houses a strong magnet which can be activated by turning the switch. Position the magnetic stand on a weighted steel base plate or metal desk and rotate the dial counter-clockwise to engage the magnet. We offer multiple styles of magnetic stands, but these videos show a couple options. Flexible Magnetic Stand   The M11 Flexible Magnetic Stand is ideal for probe holders and other lightweight objects. The flexible arm bends like a snake and locks into position with a flick of the control lever. Here we show you how easy it is to set it up. Magnetic Stand with Adjustment Arm The M9 Magnetic Stand has an adjustment arm. We'll show you how to easily position it and set it in place. The magnetic base can be easily engaged or disengaged so that you can mount the stand firmly to a metal desk or weighted metal base plate.   See All Magnetic Stands  
  8. Front Filling Nanofil Syringe
    May 22, 2013
    In this video, Mike Pizza demonstrates how to front fill a Nanofil syringe using MicroFil.   More Info
  9. Micro Injection Setup 101
    April 29, 2013
    When it comes to setting up microinjection systems, the options appear endless. The pictures below give some broad suggestions on how you might set up your own system. Keep in mind that many parts are interchangeable depending on your needs or preferences. In general, you will need a stereo microscope on a stand, a light source, one or two micromanipulators with stands, and one or two injection systems. The following images show various setups for microinjection, and all the WPI part numbers are included for easy reference. Remember, when you set up your own system, choose the parts that fit your needs. For example: M10 or the M9 magnetic base could be used.
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