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Blog
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December 08, 2023Leakages of your syringe can be extremely detrimental to the success of your fluid administration and overall application quality. Listed here are seven cases showing why your syringe might experiencing leakage, and how to overcome this...more
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December 07, 2023Microfluidics is an ever-expanding practice involving fine-tuned control of ultra-low volumes of fluid, generally within the nanoliter to microliter scale. This area of study has considerably shifted approaches to scientific and industrial discovery. Particularly, utilizing a microfluidics-based approach in the realm of drug development has shown great promise in catalyzing movement to clinical trials by allowing for biological processes to be studied ex vivo, using more relevant human tissue models. Listed are just some of the means by which microfluidics is improving drug development processes...more
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November 20, 2023Micromanipulators are widely used in cell biology, neurobiology, microelectronics, and microsurgery. Micromanipulators enable researchers to perform intricate tasks with high accuracy and stability, making them indispensable laboratory tools in a variety of applications...more
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November 13, 2023
Let’s take a look at how to set up a Digital Rat/Mouse, Neonatal Rat Stereotaxic frame. In a few steps you will be up and running...more
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November 10, 2023
SARASOTA, Fla., November 10, 2023 /PRNewswire/ -- World Precision Instruments (WPI), a leading provider of high-quality laboratory instruments and equipment for basic research and drug development, is proud to announce the establishment of its Scientific Advisory Board (SAB). Comprised of renowned experts in various scientific disciplines, the SAB will play a crucial role in guiding and advancing WPI's commitment to innovation and excellence in scientific research...more
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November 08, 2023
Transepithelial/transendothelial electrical resistance (TEER) measurement is one of the most used practices to evaluate cellular health, such as cellular confluence, barrier integrity, or barrier function of cellular monolayers grown onto multiwells. The TEER measurement using WPI’s Epithelial Voltohmmeter (EVOM) is considered the gold standard because of its reliable measurements and numerous literature citations using various cell types. The EVOM™ Manual and EVOM™ Auto along with different choices of electrodes (STX4, STX HTS high throughput screening, EndOhm chambers, and multielectrode array for EVOM™ Auto) allow researchers to perform and analyze cell samples in 6, 12, and 24 removable inserts and 24 and 96 HTS multiwell plate formats. The major challenges researchers may encounter while performing studies to capture TEER measurement include:
· Unstable read outs
· Out of range values
· Inconsistent measurements...more -
November 06, 2023
Transepithelial Electrical Resistance (TEER) is a widely used technique in the life sciences fields and therapeutic development. It measures the electrical resistance across a cell monolayer, providing information about the integrity and functionality of epithelial barriers. TEER has proven to be a valuable tool in various fields, including drug absorption studies, tissue engineering, and disease modeling. This article aims to explore the benefits of TEER and its applications in different research areas...more
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November 03, 2023
EVOM™ Auto High Throughput (HTS) Transepithiel Electrical Resistance (TEER) Measurement System with 24 and 96 transwell capability can switch between different 24 and 96 HTS well plates by using matching electrode arrays and plate positioners. Here we demonstrate how to switch to a 24 transwell plate after using a 96 transwell plate. ...more
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November 02, 2023
EVOM™ Auto is WPI’s latest high throughput screening TEER measurement system with 24 and 96 HTS transwell plate measurement capability, and it offers easy options for switching between different plates. I will show you how to setup it up. The Interface Unit is the controller that establishes communication between the EVOM™ Auto software and the autosampler. ...more
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October 31, 2023
EVOM™ Auto High Throughput (HTS) Transepithiel Electrical Resistance (TEER) Measurement System with 24 and 96 transwell capability can switch between different 24 and 96 HTS transwell plates by using matching electrode arrays and plate positioner. Here we demonstrate how to install a well plate. ...more