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Animal Physiology
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May 06, 2022
The ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. It has three modes of operation, which we discuss here.
Normal mode compares the temperature and the setpoint for PID control. Adaptive mode is ingenious. It uses the monitored animal temperature and the actual plate temperature to define an offset value which is used to adjust the PID parameters. That offset is recalculated at a set interval for extremely precise control. Shutdown mode is a fail safe that shuts the unit down if the plate temperature reaches a defined setpoint (like 45ºC) that would endanger the animal.
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May 04, 2022
The ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. Here we show you how to reset the factory defaults on your ATC2000.
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May 02, 2022
The ATC2000 is a low noise heating system for maintaining animal body temperature during expiremental procedures.
Here are some common issues you may encounter:
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April 29, 2022
The ATC-2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. The ATC-2000 uses a digital PID controller to regulate the application of power to the heating plate to achieve the desired temperature at the monitored sensor. PID stands for Proportional, Integral and Differential. If the factory default PID settings do not adequately stabilize the system, you can manually adjust the PID parameters. WPI doesn't reccomend changing these parameters manually unless you are familiar with the functions of each PID parameter.
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April 27, 2022
ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. Here we will look at how to adjust the basic configuration parameters. From the configuration menu, you can:
- Adjust the set point temperature
- Set the high and low alarm limits
- Enable/disable the audible alarm
- Adjust the three temperature offsets
- Enable adaptive mode and setup the adaptive interval
- Change the shutdown temperature setpoint
You can use the same procedure to adjust any ATC2000 configuration parameter, regardless of which parameter you’re adjusting.
- Press the Config button to access the Configuration menu. Press the Config button again to toggle to the parameter you want to adjust.
- Then use the Up or Down button to make an...more
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April 25, 2022
ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. The ATC2000 has three temperature sensors. One is located in the heated plate, and the other two can be plugged into the RTD and TC input ports. The ATC2000monitors all three temperature readings. You can choose which of the three the unit will control. The ATC2000 then heats (or stops heating) the plate to keep the controlled temperature within the alarm limits.
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April 22, 2022
ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. The temperature controller provides electrically quiet control over the heating plate, so that you can place the animal directly onto the heating plate. Here’s how to set up the system.
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April 20, 2022
ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. Here we will look at the main display on the front panel to see what information is available and the three operational modes.
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April 18, 2022
The ATC 2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. Here are five reasons to choose the WPI Animal Temperature Controller. WPI's Adaptive control is unique in the industry, giving you precision control without the need for complex programming when it counts. Simple to setup. Stable control. No local hotspots.
1. ELECTRICALLY QUIET:
The DC heater is extremely quiet in terms of electromagnetic radiation. This is essential in electrophysiological recordings which are very sensitive to electromagnetic interference.
2. PRECISE & STABLE CONTROL:The controller uses proportional, integral, and differential (PID) technology in adjusting the DC voltage output. Compared with switched on/off type controllers, PID controllers provide a much more precise and stable control of temperature. The PID approach is also more immune to the variation of the experimental conditions such as change in animal size and unexpected disturbances.
3. OPTIONS FOR CONTROL:The controller has three temperature sensing inputs that give you options for control.
- The resistive temperature device (RTD) probe input can be used to monitor an RTD rectal probe to control the animal temperature or to monitor ambient temperature, induction chamber temperature or any other temperature.
- When using a thermocouple probe, the thermocouple (TC) probe input can be used just like the RTD input. (TITLE: A T type thermocouple must be used.)
- The heater plate also has an internal temperature sensor. The ATC2000 monitors this sensor to prevent the localized hot spots under animal.
4. ADAPTS TO DIFFERENT SIZE ANIMALS AUTOMATICALLY:Adaptive mode, one of three operational modes, uses the temperature of the heated plate and the temperature of the subject to automatically adjust the PID parameters, regardless of the animal’s size. This approach is less prone to overshoot, but somewhat slower than normal mode to stabilize, depending on the sampling rate used.
5. ELIMINATES LOCAL HOTSPOTS:The plate’s internal temperature sensor prevents localized hot spots under the animal with maximum temperature stability. The Shutdown mode is a fail-safe mode used if the plate temperature ever exceeds your shutdown set point. (TITLE: By default, the shutdown set point is 37ºC.)
When you need precise temperature control for small animal surgery, you need WPI’s ATC2000...more -
February 04, 2022
Overview of the MICRO-ePUMP
Designed to simplify intracellular injection and a variety of other microinjection tasks, the MICRO-ePUMP uses carefully regulated air pressure for injecting cells with fluid. Injected volumes range from picoliters to nanoliters. Timing, injection pressure and compensation pressure are adjusted independently using the touch screen interface. Time intervals can range from 2 seconds down to 10 ms or less, depending on the injection pressure setting. The injection pressure interval is triggered using the foot switch.
The MICRO-ePUMP is designed to inject very small quantities of fluids, such as drugs, into cells or small organelles. Two different positive pressures may be applied with a precision timing circuit that switches between the two pressure automatically.
- The port supplies positive pressure for high-pressure ejection.
- The pressure port maintains a low positive “compensation” pressure to the injecting...more
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July 16, 2018
This 900A video series of 6 videos is designed to help familiarize you with the basic operation of the 900A Micropressure System. The 900A was designed for measuring pressures in kidney tubules, and it has many applications. It has recently been used for measuring...more -
May 01, 2014
The 900A is designed to measure hydrostatic pressure in small vessels and cells. Pressure ranges of -200 to +400 millimeters of mercury can be measured with stability and accuracy. The system's sensing element is an electrolyte-filled glass microelectrode with a tip diameter range of 2 to 5 microns. Pressures of electrolyte solutions are measured by maintaining a salt concentration gradient at the tip of the sensing electrode in dynamic equilibrium by applying an equal air pressure inside the microelectrode. The pressure reading appears on the front panel display and via the BNC recorder output. Because the piezo electric pressure controller uses external pressure and vacuum sources, pressures lower than -200 to greater than +400 mm Hg can be quickly and accurately measured at the microelectrode tip.
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