Low Toxicity Silicone Adhesive
Ideal for neuroscience applications, nerve studies and more
- Bio-compatible adhesive for live tissue and nerve studies
- Pre-mixing tips simplify use (Includes 10 mixing tips)
- Medium strength adhesion
- Low toxicity
- Rapid curing silicone adhesive, cure on contact
- Cures without producing heat
- The kit comes with (2) cartridges of 2 part silicone
- Volume discounts - Save up to 15% off the retail price when you buy 10 or more!
- Kwik-Sil dries clear; Kwik-Cast dries green
- Kwik-Sil dries a little faster than Kwik-Cast
- Low toxicity
- Rapid cure time
- Neuroscience and nerve studies
- Biomedical applications
Kwik-Sil and Kwik-Cast silicones have very low toxicity before, during and after curing. The by-product of curing is a small amount of hydrogen gas, which is much less toxic to cells than acetic acid or alcohol from traditional RTV silicone systems.
Kwik-Sil and Kwik-Cast curing speed is hundreds of times faster than traditional RTV silicones. A curing time of a few minutes at room temperature is especially useful for encapsulation of live tissue or implanting into a live animal. Unlike many vinyl-based silicones in which the platinum complex catalysts are easily poisoned by contamination from amines and animal tissue, Kwik-Sil and Kwik-Cast are not sensitive to contamination from animal tissue.
Kwik-Sil™ is a translucent, medium-viscosity silicone adhesive, developed for chronic peripheral nerve studies such as anterograde tracing with fluorescent indicators or electrode recording. Good adhesion and mechanical properties (tear strength and elongation) allow days of study without breaking of the bonding. Curing speed is very reproducible.
Kwik-Cast™ is a very low viscosity silicone sealant developed to embed peripheral nerves with electrodes for acute multi-fiber recordings. It flows easily, filling the small spaces around the nerve and leaving no channels through which peritoneal fluid can travel and thus short the nerve/electrode contact. Equally important is the ability of the material to flow into itself and create one continuous mass from underneath the nerve all the way to the top of the nerve/electrode contact to ensure long-term recording stability. Kwik-Cast is color-coded to make the mixing foolproof. The catalyst is yellow and the base is blue. When uniformly mixed, it is green. Kwik-Cast can be applied and cured underneath mineral oil. After recording, electrodes are easily recovered due to the low tear strength. The slight longer curing time (approx. 3 minutes) makes it more suitable for stationary preparations and in vitro tissue studies.
New Tip Design
Kwik-Sil and Kwik-Cast now come with a new tip design. The new tip is engineered to minimize leakage.
The properties of this bio-compatible adhesive make it exceptionally useful for neuroscience applications, peripheral nerve studies and similar biomedical applications. These silicone elastomers also eliminate the mess and time involved in pre-mixing other commonly used formulations (such as Wacker SilGel® and Sylgard®). Each silicone elastomer is packaged in a double barrel syringe and is automatically mixed when pressed out of the mixer tip provided. It can then be applied directly to the tissue without further mixing. The curing time of these silicone adhesives is short, reliable and reproducible. This eliminating potential costly guesswork when using other tissue adhesives. The curing process does not produce any heat, which can cause tissue damage. WPI's silicone elastomers are much less toxic than dental silicone, because they contain no surfactant additives.
The silicone adhesive inside the syringes cannot be sterilized by any means including UV, gamma, H2O2, autoclaving or EtO.
The exterior and the tips can be immersed in or wiped with 70/30 alcohol or you can use a liquid sterilant like Cidex OPA (WPI P/N 7364-4) or Rapicide OPA (WPI P/N 504611).
KWIK-CAST & KWIK-SIL Specifications
KWIK-CAST Silicone Casting Compound (two 5-mL syringes)
KWIK-SIL Silicone Adhesive Compound (two 5-mL syringes)
|MIX RATIO||1 to 1||1 to 1|
|WORKING TIME||< 5 minutes*||4 minutes|
|SETTING TIME (ROOM TEMP., 1:1 RATIO)||5–10 minutes**||<10 minutes|
|CURE TIME||~15 minutes|
|GUARANTEED SHELF LIFE AT 23 °C||6 months||6 months|
|VOLUME||5 mL||5 mL|
|NUMBER OF MIXING TIP||10||10|
|DEAD VOLUME OF THE MIXING TIP||<0.12 mL||<0.12 mL|
|AFTER CURING 24 HOURS:|
|TEAR STRENGTH, PPI||90||44|
|DUROMETER (SHORE A-2)||30||36|
|VOLUME RESISTIVITY, W/CM||1x1015||1x1015|
* 3 minutes average with about 90 seconds of liquidity
** no longer mixable at this point
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Q: I want to use Kwik Sil in my "imaging" experiments in rats. How do I get rid of the bubbles completely, or at least reduce them as much as possible?
A: The bubbles are hydrogen gas that is released as a by-product of the curing process. The cure happens in such a short period that the gas can't escape. A slower cure time might help. To slow the cure process, cool the material before mixing.