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KIT, SILICON SEALANT

Name: KIT, SILICON SEALANT
Brand: Brand
SKU: KWIK-CAST
Price: 137 USD
Availability: InStock

$137.00

Prices valid in USA, Canada, and PR only.

Order code

KWIK-CAST

Prices valid in USA, Canada, and PR only.

The properties of this bio-compatible surgical adhesive make it exceptionally useful for neuroscience applications, peripheral nerve studies and similar biomedical applications. These silicone elastomers also eliminate the mess and time involved in pre-mixing other commonly used formulations (such as Wacker SilGel^®and Sylgard^®). Each silicone elastomer is packaged in a double barrel syringe and is automatically mixed when pressed out of the mixer tip provided. It can then be applied directly to the tissue without further mixing. The curing time of these silicone adhesives is short, reliable and reproducible. This eliminates potential costly guesswork when using other tissue adhesives. The curing process does not produce any heat, which can cause tissue damage. WPI's silicone elastomers are much less toxic than dental silicone, because they contain no surfactant additives.

A sterile version of this product is available as KWIK-CAST-S.

*New and Improved with Extended Shelf Life

Prices valid in USA, Canada, and PR only.

Silicone sealant ideal for neuroscience applications, nerve studies and more

Biocompatible adhesive to seal live tissues
Embed peripheral nerves with electrodes
Pre-mixing tips simplify use (Includes 10 mixing tips)
Medium strength adhesion
Low toxicity
Rapid curing silicone adhesive, cure on contact
Cures without producing heat
The kit comes with (2) cartridges of 2 part silicone
Kwik-Sil dries clear; Kwik-Cast dries green
Kwik-Sil dries a little faster than Kwik-Cast

Low Toxicity Silicone Adhesive

See for yourself why KWIK-CAST silicone adhesive is so popular for life science applications. When you are looking for a low toxicity adhesive with some elasticity and good moisture resistance, a silicone adhesive is the option of choice. When used with living tissue, an adhesive must be:

Non-toxic
Fast Curing
Able to adhere to organic and inorganic surfaces

Kwik-Sil™ and Kwik-Cast™ silicone adhesives have very low toxicity before, during and after curing. The by-product of curing is a small amount of hydrogen gas, which is much less toxic to cells than acetic acid or alcohol from traditional RTV silicones.

Kwik-Sil™ and Kwik-Cast™ have a curing speed that is hundreds of times faster than traditional RTV silicones. A curing time of a few minutes at room temperature is especially useful for encapsulation of live tissue or implanting into a live animal.

Kwik-Sil™ and Kwik-Cast™ surgical adhesives are not sensitive to contamination from animal tissue, unlike many vinyl-based silicones in which the platinum complex catalysts which are easily poisoned by contamination from amines and animal tissue.

Kwik-Sil™ vs Kwik-Cast™

Kwik-Sil Vs. Kwik-Cast

Both Kwik-Sil and Kwik-Cast are silicone adhesives, but they are a little different.

Kwik-Sil™ is a translucent, medium-viscosity silicone adhesive, developed for chronic peripheral nerve studies such as anterograde tracing with fluorescent indicators or electrode recording. Good adhesion and mechanical properties (tear strength and elongation) allow days of study without breaking of the bonding. Curing speed is very reproducible.

Kwik-Cast™ is a very low viscosity silicone sealant developed to embed peripheral nerves with electrodes for acute multi-fiber recordings. It flows easily, filling the small spaces around the nerve and leaving no channels through which peritoneal fluid can travel and thus short the nerve/electrode contact. Equally important is the ability of the material to flow into itself and create one continuous mass from underneath the nerve all the way to the top of the nerve/electrode contact to ensure long-term recording stability. Kwik-Cast is color-coded to make the mixing foolproof. The catalyst is yellow and the base is blue. When uniformly mixed, it is green. Kwik-Cast can be applied and cured underneath mineral oil. After recording, electrodes are easily recovered due to the low tear strength. The slight longer curing time (approx. 3 minutes) makes it more suitable for stationary preparations and in vitro tissue studies.

Kwik-Sil™ New Tip Design

Evom Transcellular and Paracellular Pathway of Ion or Electrical Current Flow

Kwik-Sil™ and Kwik-Cast™ now come with a new tip design. The new tip is engineered to minimize leakage.

Kwik-CAST™ Applications

Kwik-CAST™ silicone is based on technology with vinyl terminated siloxane and platinum complex catalysts. In order to cure at room temperature, special cross linkers and high catalyst concentration are used. Although the high concentration of catalysts makes these products more costly than traditional RTV silicones and less attractive for general usage, they provide an excellent value in applications for the biological research field.

Benefits

Low toxicity surgical adhesive
Rapid cure time
6 Month shelf life

Applications

Neuroscience and nerve studies
Biomedical applications

Kwik-Sil and Kwik-Cast silicones have very low toxicity before, during and after curing. The by-product of curing is a small amount of hydrogen gas, which is much less toxic to cells than acetic acid or alcohol from traditional RTV silicone sealant systems.

Kwik-Sil and Kwik-Cast curing speed is hundreds of times faster than traditional RTV silicone adhesives. A curing time of a few minutes at room temperature is especially useful for encapsulation of live tissue or implanting into a live animal. Unlike many vinyl-based silicone adhesivess in which the platinum complex catalysts are easily poisoned by contamination from amines and animal tissue, Kwik-Sil and Kwik-Cast are not sensitive to contamination from animal tissue.

Kwik-Cast™ is a very low viscosity silicone sealant developed to embed peripheral nerves with electrodes for acute multi-fiber recordings. It flows easily, filling the small spaces around the nerve and leaving no channels through which peritoneal fluid can travel and thus short the nerve/electrode contact. Equally important is the ability of the material to flow into itself and create one continuous mass from underneath the nerve all the way to the top of the nerve/electrode contact to ensure long-term recording stability. Kwik-Cast is color-coded to make the mixing foolproof. The catalyst is yellow and the base is blue. When uniformly mixed, it is green. Kwik-Cast silicone sealant can be applied and cured underneath mineral oil. After recording, electrodes are easily recovered due to the low tear strength. The slight longer curing time (approx. 3 minutes) makes it more suitable for stationary preparations and in vitro tissue studies.

Curing Time

The properties of this biocompatible adhesive make it exceptionally useful for neuroscience applications, peripheral nerve studies and similar biomedical applications. These silicone elastomers also eliminate the mess and time involved in pre-mixing other commonly used formulations (such as Wacker SilGel® and Sylgard®). Each silicone elastomer is packaged in a double barrel syringe and is automatically mixed when pressed out of the mixer tip provided. The silicone sealant can then be applied directly to the tissue without further mixing. The curing time of these silicone adhesives is short, reliable and reproducible. This eliminating potential costly guesswork when using other tissue adhesives. The curing process does not produce any heat, which can cause tissue damage. WPI's silicone elastomers are much less toxic than dental silicone, because they contain no surfactant additives.

The silicone adhesive inside the syringes cannot be sterilized by any means including UV, gamma, H2O2, autoclaving or EtO. The exterior and the tips can be immersed in or wiped with 70/30 alcohol or you can use a liquid sterilant like Cidex OPA (WPI P/N 7364-4) or Rapicide OPA (WPI P/N 504611).

NOTE: Due to supply constraint, this product is currently non-returnable/non-refundable. For details, please refer to the WPI Terms & Conditions.

More Information
SKU	KWIK-CAST
Options	Sterile

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MIXING TIPS, 10/PK

$50.00

Kwik-Sil/Kwik-Cast Instruction Manual

Video

5 Reasons KWIK-SIL & KWIK-Cast Adhesive are Ideal for Neuroscience Application

KWIK-SIL versus KWIK-Cast, What's the Difference

FAQ

I want to use KwikSil surgical glue in my "imaging" experiments in rats. How do I get rid of the bubbles completely, or at least reduce them as much as possible?

The bubbles are hydrogen gas that is released as a by-product of the curing process. The cure happens in such a short period that the gas can't escape. A slower cure time might help. To slow the cure process, cool the material before mixing.

Can the adhesive be removed safely from rodent fur after use after it has cured?

If Kwik-Cast/Sil is applied to rodent fur, the cured adhesive can be removed from fur. Just gently and slowly pull the cured adhesive away from fur. Naturally, there are oils on fur and hair.

KWIK-CAST & KWIK-SIL Specifications

KWIK-CAST Silicone Sealant (two 5-mL syringes)

KWIK-SIL Silicone Adhesive Compound (two 5-mL syringes)

	Kwik-Sil	Kwik-Cast
MIX RATIO	1 to 1	1 to 1
WORKING TIME	< 5 minutes*	4 minutes
SETTING TIME (ROOM TEMP., 1:1 RATIO)	5–10 minutes**	<10 minutes
CURE TIME	~15 minutes	~15 minutes
VISCOSITY, CPS	15,000	10,000
GUARANTEED SHELF LIFE AT 23 °C	6 months	6 months
VOLUME	5 mL	5 mL
NUMBER OF MIXING TIP	10	10
DEAD VOLUME OF THE MIXING TIP	<0.12 mL	<0.12 mL
NOTE	This is the consistency of pourable silicone rubber.	This is the consistency of chocolate syrup.
AFTER CURING 24 HOURS:
TEAR STRENGTH, PPI	90	44
ELONGATION %	650	60
DUROMETER (SHORE A-2)	30	36
COLOR	translucent	green
VOLUME RESISTIVITY, W/CM	1x10¹⁵	1x10¹⁵

* 3 minutes average with about 90 seconds of liquidity

** no longer mixable at this point

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