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504651
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Our reusable biopsy punches are multi-purpose sampling tools designed with a retractable cutting cannula. They are easy to operate, efficient, safe, fast and precise. Our punches consists of a razor sharp stainless steel cutting tip. It is designed to cut, retrieve and store the cored samples from a source materials. The source could be skin, tissue, gels, paper, cloth, leaves, paint chips, films or other thin, soft substrates. The biopsy punches are recommended as a DNA sampling tool and are also ideal for forensic use and laboratory sampling applications. The punches come sterile and are individually wrapped. They were sterilized using ethylene oxide.
The WPI Limited Reuse Biopsy Punch is a reusable, autoclavable stainless steel instrument designed to cut, core, and retrieve precise samples from skin, tissue, gels, agar, and other soft substrates. Featuring a retractable stainless steel cutting blade, it is available in 15 sizes from 0.35 mm to 8 mm and is supplied individually sterile-packed. Unlike fully disposable biopsy punches, it can be cleaned and autoclaved for multiple uses, reducing cost per sample while maintaining consistent cutting performance. Common applications include DNA and tissue sampling, forensic evidence collection, laboratory sample preparation, and microfluidics chip fabrication.
| Order code | Size (mm) | ID (mm) | OD (mm) | Wall thickness (mm) |
| 504638 | 0.35 | 0.33 | 0.63 | 0.15 |
| 504528 | 0.5 | 0.5 | 0.8 | 0.15 |
| 504529 | 0.75 | 0.77 | 1.07 | 0.15 |
| 504646 | 1 | 0.96 | 1.26 | 0.15 |
| 504530 | 1.2 | 1.2 | 1.5 | 0.15 |
| 504647 | 1.5 | 1.5 | 1.9 | 0.2 |
| 504531 | 2 | 2 | 2.4 | 0.2 |
| 504648 | 2.5 | 2.5 | 2.9 | 0.2 |
| 504649 | 3 | 3 | 3.4 | 0.2 |
| 504650 | 3.5 | 3.5 | 3.9 | 0.2 |
| 504651 | 4 | 4 | 4.4 | 0.2 |
| 504532 | 5 | 5 | 5.5 | 0.25 |
| 504533 | 6 | 6 | 6.5 | 0.25 |
| 504534 | 7 | 7 | 7.5 | 0.25 |
| 504535 | 8 | 8 | 8.5 | 0.25 |
0.35–1mm - Microfluidics inlet punching (PDMS chambers), small-diameter DNA/tissue sampling
1.2–2.5mm - Standard skin/tissue biopsy sampling, ear tagging
3–5mm - Larger tissue cores, agar/gel plug transfers
6–8mm - Bulk sample transfers, larger substrate coring
Unlike standard disposable punches, these limited reuse biopsy punches may be cleaned between uses and autoclaved according to laboratory protocols, helping reduce operating costs while maintaining sampling precision.
| Limited Reuse | Disposable |
| Multiple uses after cleaning | Single use only |
| Lower long-term cost | Higher recurring cost |
| Autoclavable | Not reusable |
| Ideal for research labs | Ideal for clinical procedures |
| Better for frequent sampling | Better for one-time sterile procedures |
Surgical Instrument Care and Handling Instructions

Biopsy Punch
| Specifications | |
| Material | PP - body 304 stainless steel - cutting cannula (tip) |
| Packing | individually wrapped |
| Sterilization | Autoclaving for 20 minutes at 250°F. |
| Patent | US patent pending no. 14/335,975 |
| Origin | Taiwan |
I am using the 0.75 mm WPI punch for punching flow inlets in microfluidics chambers molded of PDMS (polydimethylsiloxane). I have made around 75 hole punches with a single unit into PDMS, the blade and the extractor still work perfectly, though the extractor button sticks slightly. I find the blade to be noticeably sharper than the Harris equivalent, as well as being more ergonomic, in my opinion, with the feel of a pen or pencil in one's hand. R.P., UNC.
Al Nahas, K., Cama, J., Schaich, M., Hammond, K., Deshpande, S., Dekker, C., … Keyser, U. F. (2019). A microfluidic platform for the characterisation of membrane active antimicrobials. Lab on a Chip, 19(5), 837–844. https://doi.org/10.1039/C8LC00932E
Ionescu, A., Zahavi, E. E., Gradus, T., Ben-Yaakov, K., & Perlson, E. (2016). Compartmental microfluidic system for studying muscle–neuron communication and neuromuscular junction maintenance. European Journal of Cell Biology, 95(2), 69–88. https://doi.org/10.1016/j.ejcb.2015.11.004
Wamsley, C. E., Kislevitz, M., Barillas, J., Basci, D., Kandagatla, V., Hitchcock, T., … Kenkel, J. (2021). A Single-Center Trial to Evaluate the Efficacy and Tolerability of Four Microneedling Treatments on Fine Lines and Wrinkles of Facial and Neck Skin in Subjects With Fitzpatrick Skin Types I-IV: An Objective Assessment Using Noninvasive Devices and 0.33-mm Microbiopsies. Aesthetic Surgery Journal, 41(11), NP1603–NP1618. https://doi.org/10.1093/ASJ/SJAB052
Kislevitz, M., Wamsley, C., Bartels, M., Lu, K. B., Li, X., Pinch, S., … Akgul, Y. (2021). Clinical Translation of Scarless 0.33-mm Core Microbiopsy for Molecular Evaluation of Human Skin. Aesthetic Surgery Journal, 41(11), NP1710–NP1720. https://doi.org/10.1093/ASJ/SJAA332
Kislevitz, M., Lu, K. B., Wamsley, C. E., Parsa, S., Hoopman, J. E., Kenkel, J. M., & Akgul, Y. (2021). Bipolar Fractional Radiofrequency Treatment of Suprapatellar Skin Assessment Using Noninvasive Devices and Microbiopsy. Aesthetic Surgery Journal. https://doi.org/10.1093/ASJ/SJAB210
Kislevitz, M., Lu, K. B., Wamsley, C., Hoopman, J., Kenkel, J., & Akgul, Y. (2020). Novel Use of Non-Invasive Devices and Microbiopsies to Assess Facial Skin Rejuvenation Following Laser Treatment. Lasers in Surgery and Medicine, 52(9), 822–830. https://doi.org/10.1002/LSM.23233
15 sizes, from 0.35mm to 8mm, each with its own order code (e.g., 504638 for 0.35mm, 504535 for 8mm). Full inner diameter, outer diameter, and wall-thickness specs are in the table above.
Yes. After each sample, clean the tip by coring blank filter paper, then rinse with ethanol or compressed air. Between procedures, autoclave for 20 minutes at 121°C (250°F).
The stainless steel cutting surface is designed for thin, soft substrates like skin, tissue, gels, paper, cloth, leaves, paint chips, and thin films.
Yes, WPI recommends it as a DNA sampling tool, and it's also used for forensic sample collection and general laboratory sampling.
WPI's Cutting Mats for Biopsy Punches are sized to support the sample during cutting and to make rinse-cleaning between extractions easier.
Yes, it's commonly used to punch flow inlets in PDMS microfluidic chambers. One WPI customer reports roughly 75 clean hole-punches from a single 0.75mm unit with the blade still sharp.

$11.00
Multiple SKUs
Multiple SKUs
When you need to quickly take minimally invasive, small samples, the biopsy punch is an easy choice. The biopsy punch is a hand held, pencil-shaped instrument with a slender, pencil-like body. It is lightweight with a hollow, circular, stainless steel, cutting tip.
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Get yours while you can.