Portable EVOM™ Manual Simplifies TEER Measurement

WPI's EVOM Technology has been cited in thousands of peer-reviewed research articles. You've placed your trust in our TEER measurement line for nearly 40 years as the premiere innovator and manufacturer of  EVOM meters, REMS, and Millicell ERS2. EVOM Manual is the original and still the gold standard in TEER measurement.

TEER is used for evaluating physiological properties like cellular confluence or monolayer integrity, barrier function, and 3-D tissue function. The EVOM™ Manual qualitatively measures cell monolayer health and quantitatively measures cell confluence by determining an increase or a plateau in tissue resistance detected using our innovative EVOM™ technology. The EVOM™ Manual produces a low AC current that avoids electrode metal deposits and is specially designed for the non-destructive testing of epithelial monolayer confluence in cell cultures. Additionally, resistance readings are unaffected by membrane capacitance or membrane voltage. WPI’s state of the art EVOM™ technology provides you with real time valuable feedback during experiment measurements.

Automated measurement of tissue resistance in cell culture microplates provides the advantages of speed and precision, minimizes the chances of contamination, and ensures the rapid availability of measured resistance data. EVOM™ Auto applies a 12.5 Hz square wave current with switching polarity, which mitigates the chances of charging the sample and nullifies the chances of measurement technique having any adverse effects on the sample. Therefore, it is considered non-invasive measurement. EVOM™ Auto is designed for the non-destructive, high throughput screening of epithelial monolayer confluence and barrier function studies in cell cultures.

EVOM™ Manual with the help of different electrode options can measure cell layer resistances in different transwell formats (6, 12, and 24-well) removable inserts or in 24 and 96-well high throughput screening (HTS) plates. EVOM™ Manual can store data in an USB flash drive, which can be easily accessed by a computer.

BENEFITS OF EVOM™ MANUAL

  • Store Data & Save Time
    Eliminates errors and reduces processing time with stored data
  • Data Precision
    Easy calibration and verification
  • Blue icon of a cloud with a cube inside a circle on a white background
    Auto Tracking
    Smart touchscreen interface with live data display and automatic data logging
  • Hands Free Recording
    Footswitch for easy data recording
  • Blue icon of a keyboard inside a circle on a white background
    Auto Resistance Ranges
    Analyze different cell/tissue types
  • Blue logo with a wavy line inside a circle on a white background
    Low Noise Design
    Greater resolution and accuracy
  • Portable/Small Footprint
    Transport between experiment easily and save bench space
  • Blue icon of a battery with a lightning bolt and a clock inside a circle on a white background
    Auto Save & Data Recovery
    Data saved when the battery is low

ELECTRODE OPTIONS

EVOM™ Manual is compatible with avariety of electrodesthat match your requirements for 6,12, 24, 96-well Transwells or HTS plates. Electrodes are user selectable with EVOM ™ Manual.

  • STX4

    • Greater measurement precision than STX2/STX3
    • Hands-free operation
    • Cable blocks RF interference
    • Low media volume
    • Longer life with replaceable blades
    • No chloriding necessary (coated tips)

  • STX HTS

    • Smaller tip size than the STX2 electrode
    • Constructed for durability
    • Fits neatly into the keyhole-shaped filter well
    • Electrode design reduces chance of contamination
    • Use with specific 24-well plates

  • ENDOHM

    • Stability and reproducibility superior to the STX2 electrodes to 1% tolerance
    • Can be used with 6, 12 or 24-well plates with removable inserts
    • Symmetrical electrode pattern disperses test current uniformly
    • Proven history

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Product & Accessories

Build a complete TEER measurement workflow with accessories and complementary products designed for use with the EVOM™ Manual. From warming plates to cell culture inserts, these tools help streamline experiments, improve consistency, and support reliable barrier integrity measurements across a wide range of research applications.

See All Manual TEER Products

More Information

Get the most from your EVOM™ Manual with resources designed to support every stage of your research. Explore compatible electrodes and accessories, learn how to select the right configuration for your application, and access detailed product information to help ensure accurate, reliable TEER measurements.