Micromanipulator

The Ultimate Guide to Micromanipulators

by Brittany Crafton

Micromanipulators are an important tool used to execute minute, fine-tuned movements critical for various applications including microinjection into cells or tissue, microscopy, as well as for research involving biological and nano-engineering implementation. Before selecting a micromanipulator, consider the following to choose the best option for your application:

Application and Requirements

Identify the specific movements you need the micromanipulator to perform. Different applications may demand certain properties, such as level of precision, configurations (range of movement along an x, y, z, or even a fourth dimensional axis), or external controller functionality.

Precision and Accuracy

Micromanipulators vary by their level of precision, often referred to in terms of resolution. Greater resolution allows you to achieve incredibly small increments of movement per turn of the manipulator dial, essential for many tedious micron- and nano- scale applications.  

Configurations/Range of Motion

The necessary operation range is an important factor when choosing the right micromanipulator. Be sure to assess your working area and set-up. Are you using a micro syringe or glass capillary? What is the length of each of these components versus the distance to your base target position? Are you performing micro-soldering? Tetrode arrays? What is the extreme angle you are working at?

While some micromanipulators are made to perform fine linear movements, others offer rotational, 3-dimensional, or even a virtual 4-dimensional movements. Further, some micromanipulators are offered with an adjustable base to alter your working angle, a beneficial feature especially when needing to access difficult configurations in any micro-engineering work. Additionally, be sure to assess whether you require a left/right-handed configuration, or if you require a dual set-up.

Control System

Micromanipulators can be operated manually, with an external trigger system (for example, a computer), an isolated or integrated controller system (for example, a motorized micromanipulator), or a combination. To minimize error, it is often best to avoid manual manipulation if you require sub-micron movements. Some of WPI’s most popular manual manipulators include:

o   M3301 WPI Manual Micromanipulator
o   KITE-M3 Kite Manual Micromanipulator with Tilt Base
o   SU-MP85  Classic Micromanipulator

Popular motorized manipulators include:
o   SU-MP285 Motorized Micromanipulator System
o   SU-TRIO235 Trio 3-Axis Motorized Micromanipulator
o   SU-QUAD Quad 4-Axis Motorized Micromanipulator

Ergonomics and User Interface

Some micromanipulators can be complex to operate. Be sure to assess the ease-of use versus your application type. Some micromanipulators are not made to have smooth turns per knob adjustment, which may result in over-advancing along your axis, especially at the micro-scale. Features such as easily accessible manipulator knobs that are straight-forward in their operation, as well as do not interfere with your working field are beneficial.  

Load Capacity

How much force will be applied during your application? For example, will you be drilling into a medium that will resist the manipulator? Identify the load or force that the manipulator will endure to choose the appropriate model to avoid overloading and damaging the device.

Compatibility

Be sure that the micromanipulator you choose fits into or onto your working area, whether it is being used on a bench space, or attached to a larger system. If your manipulator is too large, for example, this may interfere with your visibility when working under a microscope.

Flexibility and Versatility

Determine whether you will be using your micromanipulator in various set-ups, and how it may be adapted. Can you use your manipulator both left and right-handed? If working on a pressure-adjusting microscope or tabletop, the placement of a micromanipulator must be carefully determined. What future projects may alter how you use your micromanipulator? These factors are important when considering which is the right micromanipulator for you!

Stability and Vibration Control

Like the previously mentioned stabilizing microscope or tabletop set-ups, some applications require the micro manipulation set-up to account for any de-stabilizing environmental factors like room pressure or temperature change, or external vibration. Maintaining stability is of utmost importance for achieving the best possible results for any application sensitive to minute deviations in surface stability. Be sure to consider models that offer vibration isolation or damping features to minimize external movement of your micromanipulator.

Budget

Consider your price range and any limitations. Many budget-friendly micromanipulators are available, as well as other pricier options that offer top-of-the-line precision and functionality. Be sure to assess what your ‘must haves’ are in order to best determine the right micromanipulator for you within your budget.

Brand Reputation and Support

Be sure that the micromanipulator you decide to purchase comes from a reputable company with excellent customer service and post-sale support. Talk to a representative from WPI today to serve all your micromanipulator needs!

Safety Features

Some applications require certain fail-safes to ensure any unwanted movements may be avoided. Some safety features include:

  • Interlocks to shield the user and delicate samples
  • Automatic shutdown
  • Emergency stop controls.

Think about whether these features are required for your application to determine what is the best option for you.

Warranty and Maintenance

Make sure that the micromanipulator you choose offers warranty options, and/or maintenance support from the manufacturer. It is important to have the support needed to properly maintain your micromanipulator for the continued success of your application.

After thoroughly assessing the above, you should have a better idea of the important factors to consider when choosing the right micromanipulator for you. Reach out to our WPI specialists to see how we can help to you today!

If you have an questions, just give us a call at (866) 606-1974  or email us at [email protected].

 

 

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