Microinjection
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December 08, 2023Leakages of your syringe can be extremely detrimental to the success of your fluid administration and overall application quality. Listed here are seven cases showing why your syringe might experiencing leakage, and how to overcome this...more
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December 07, 2023Microfluidics is an ever-expanding practice involving fine-tuned control of ultra-low volumes of fluid, generally within the nanoliter to microliter scale. This area of study has considerably shifted approaches to scientific and industrial discovery. Particularly, utilizing a microfluidics-based approach in the realm of drug development has shown great promise in catalyzing movement to clinical trials by allowing for biological processes to be studied ex vivo, using more relevant human tissue models. Listed are just some of the means by which microfluidics is improving drug development processes...more
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November 20, 2023Micromanipulators are widely used in cell biology, neurobiology, microelectronics, and microsurgery. Micromanipulators enable researchers to perform intricate tasks with high accuracy and stability, making them indispensable laboratory tools in a variety of applications...more
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October 20, 2023
Micromanipulators are an important tool used to execute minute, fine-tuned movements critical for various applications including microinjection into cells or tissue, microscopy, as well as for research involving biological and nano-engineering implementation. Before selecting a micromanipulator, consider the following to choose the best option for your application:...more
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October 13, 2023
Cleaning laboratory syringes helps prevent contamination and ensures accurate dosing. You should always adhere to the protocols of your institution and the manufacturer of your syringe. Specific cleaning requirements may vary based on the intended use of the syringe, its material composition , and the sample fluid introduced. Here is a typical protocol for cleaning a laboratory syringe...more
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August 31, 2023
Choosing the right syringe type depends on the specific application and the requirements of your task. Syringes come in various sizes, materials, and designs, each suited for different purposes. Here are some factors to consider when selecting a syringe type...more
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August 29, 2023
Deciding which syringe pump is best for your application involves factors like the flow rate, number of channels, and precision that you require to select and appropriate system. Use a syringe pump when manual syringe handling will negatively impact the delivery of your sample, and to precisely regulate the rate of fluid dispensed from a syringe. These pumps are utilized in diverse areas, including biomedical or chemical applications, general research, healthcare, and in industrial settings. Below is a guide to assist in deciding which syringe pump is most suitable for you:...more
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August 15, 2023
WPI’s FluoroDish™ cell culture dishes are optimally designed for a wide variety of cell culture and embryology experiments including high resolution imaging, live cell imaging, electrophysiological recordings of fluorescently tagged cells, and microinjection. FluoroDish™ cell culture dishes are far better than standard petri dishes, because they are designed with optical quality glass bottoms, which offer superior imaging using the latest microscopy technology. WPI’s FluoroDishes™ have been cited in over 550 peer-reviewed publications by cell culture laboratories across the world...more
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July 05, 2023
In any laboratory, having key lab supplies is almost as important as having the major equipment. Choosing a reputable supplier of these necessary supplies is as important as having quality laboratory supplies when you need them. WPI wants to be your partner in early drug discovery, and we stock a wide variety of lab supplies, many of which can ship the same business day. Having a variety of lab supplies ready to ship makes us a dependable research partner. Here are some of the popular supplies that we keep on hand to meet your needs for your upcoming experiment...more
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June 30, 2023
In any laboratory, having key lab supplies is almost as important as having the major equipment. Choosing a reputable supplier of these necessary supplies is as important as having quality laboratory supplies when you need them. WPI wants to be your partner in early drug discovery, and we stock a wide variety of lab supplies, many of which can ship the same business day. Having a variety of lab supplies ready to ship makes us a dependable research partner. Here are some of the popular supplies that we keep on hand to meet your needs for your upcoming experiment...more
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August 05, 2022
The ATC2000 is a low noise heating system for maintaining animal body temperature during expirimental procedures. Here we show you how to use the adaptive mode on the ATC2000 system.
- Press the Config button to access the configuration menu. Press the Config button again until the adaptive mode Enable displays.
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April 28, 2022
The ATC2000 is a low noise heating system for maintaining animal body temperature during experimental procedures. The ATC2000 uses a digital PID controller to regulate the application of power to the heating plate to achieve the desired temperature at the monitored sensor. PID stands for Proportional, Integral and Differential. Here’s how PID control works:
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April 21, 2022
A PUL-1000 is a micro-processor controlled, four stage horizontal puller that is used for making glass pipettes and microelectrodes. This article defines several factors that affect the pulling of micropipette glass capillaries.
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February 04, 2022
Overview of the MICRO-ePUMP
Designed to simplify intracellular injection and a variety of other microinjection tasks, the MICRO-ePUMP uses carefully regulated air pressure for injecting cells with fluid. Injected volumes range from picoliters to nanoliters. Timing, injection pressure and compensation pressure are adjusted independently using the touch screen interface. Time intervals can range from 2 seconds down to 10 ms or less, depending on the injection pressure setting. The injection pressure interval is triggered using the foot switch.
The MICRO-ePUMP is designed to inject very small quantities of fluids, such as drugs, into cells or small organelles. Two different positive pressures may be applied with a precision timing circuit that switches between the two pressure automatically.
- The port supplies positive pressure for high-pressure ejection.
- The pressure port maintains a low positive “compensation” pressure to the injecting...more
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July 23, 2021
Do you want to take the next step in your CRISPR-CAS9 projects, making the injection of biomolecules in your cell lines more efficient? You can now increase the viability of injected embryos with WPI’s MICRO-ePORE, which offers improved repeatability and functionality for pinpoint cell penetration for targeted microinjections in transgenesis.
Improve Embryo Survival with Pinpoint Cell Penetration
Principle of MICRO-ePORE™ Technology
- Classic Microinjection of biomolecules with capillaries causes permanent damage to the cell membrane...more