TEER Measurement Systems

InResearcher takes manual TEER measurments with STX electrode and EVOM2. epithelial cell research, there are different types of cells which are typically cultured. We will focus on epithelial cells. Epithelial tissue lines the surface and cavities of an organ. Epithelium includes your skin tissue, but it also lines the alimentary canal, organs and blood vessels. Epithelial cell cultures may be used for drug discovery or other applications that explore the transport or diffusion of a substance through an epithelial monolayer. Such a tissue research study requires a confluent monolayer that completely covers the culture substrate it is grown on. 

 


Epithelial Volt/Ohm (TEER) Meter

Item#: Make Selection

EVOM2, 300523

Non-destructively test for epithelial monolayer confluence in 2D cell cultures

  • Measures trans-epithelial electrical resistance or trans-epithelilal voltage
  • Compatible with 12 and 24 well culture plate systems out of the box
  • Includes industry standard STX2 hand held “chopstick” electrodes
  • Analog output for recording resistance or voltage measurements
  • Auto ranging from 0-10 KΩ
  • Battery powered
  • Manual TEER measurement of epithelial cells in 6, 12, 24 and 96* well plates
  • BNC output for data acquisition system
  • Compatible with EndOhm chambers
  • *96-well plate measurement requires an STX100 series electrode.
  • Choose Resistance Range: 0-10 KΩ (EVOM2) or 0-100 KΩ (300523)
  • See Details for part numbers and descriptions
Unit Price: varies

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Automated TEER Measurement System

Item#: SYS-REMS

PC-controlled high throughput TEER measurement for epithelial monolayerAutomates TEER measurement and data logging for use with HTS well plates

  • PC controlled positioning
  • Data acquisition in LabView
  • Manufacturer specific electrodes available for 24 and 96-well HTS plates
  • Plate configuration files and sample sequences are user definable
  • Two user-defined rinse locations
  • Manual mode 
Unit Price: 25405.00

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Replacement Endohm Cable

Item#: 53330-01
  • Compatible with EVOM2
Unit Price: 161.00

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Chopstick Electrode Set for EVOM2

Item#: STX3
  • Adjustable width double electrodes
  • 1mm thick
  • Use in cell culture wells
Unit Price: 346.00

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Electrode Adapter for EVOM2

Item#: 3993
  • Use with electrodes with 2 mm pins
Unit Price: 192.00

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Chopstick Electrode Set for EVOM2, 4mm

Item#: STX2
  • 4mm fixed width double electrodes
  • 1mm thick
  • Use in cell culture wells
Unit Price: 268.00

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Test Electrode for EVOM2

Item#: 91750
  • Use with EVOM2
  • 1000 ohm resistor
Unit Price: 22.00

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Cell Culture Cup Chambers for TEER Measurement

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ENDOHM-12,  ENDOHM-24SNAP, ENDOHM-6

For TEER measurement of epithelial and endothelial cell cultures

  • Compatible with EVOM2
  • Improved accuracy of 1-2 Ohm
  • Sterilize with EtO, alcohol, or a bactericide
  • Choose Culture Cup: 12mm (ENDOHM-12), 24mm (ENDOHM-24SNAP) or 6mm (ENDOHM-6)
  • See Details for part numbers and descriptions
Unit Price: 1065.00

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Ussing System for Epithelial Research

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USS1L, USS1S, USS2L, USS2S, USS3L, USS3S, USS4L, USS4S, USS5L, USS5S, USS6L, USS6S, USS7L, USS7S, USS8L, USS8S

Non-destructive TEER measurement for epithelial tissue

  • Direct connect low-resistance electrodes
  • Simple operation, easy to control temperature and clean after use
  • Luer type leak-free attachment of tubing and electrodes
  • Recessed electrode ports avoid bubble formation
  • Secure membrane holding by sharp stainless steel pins or O-ring
  • Specialized chamber adapts cell culture insert (Costar Snapwell) for monolayer cell culture
  • Chambers with rectangular openings for tubular tissues from small animals
  • See Details for part numbers and system specifications
Unit Price: varies

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HTS Electrodes for Use with the EVOM2

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STX100C, STX100C96, STX100F, STX100M

For high throughput screening (HTS) in cell culture filter plates

  • Designed for use with 24-well HTS plate (Corning Costar and BD Falcon) and with 96-well plates (Millipore)
  • Improved accuracy down to 5 Ω
  • Sterilized with EtO, alcohol or bactericide
  • Choose Plates: Corning Costar (STX100C), Corning 96 (STX100C96), BD Falcon (STX100F) or Millipore 96 (STX100M)
  • See Details for part numbers
Unit Price: 1725.00

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Replacement REMS HTS Electrode

Item#: Make Selection

REMS-24, REMS-24M, REMS-96, REMS-96C

  • Replacement electrodes for use with REMS robotic TEER measurement system
  • Choose Plate: Milipore 24 (REMS-24), Millicell 24 (REMS-24M), Millipore 96 (REMS-96) or Corning 96 (REMS-96C)
  • See Details for part numbers and descriptions
Unit Price: 2882.00

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Rechargeable Battery Pack for EVOM2

Item#: 91736
  • Rechargeable
  • 6V NiMH 2700mAH
Unit Price: 61.00

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TEER Measurement Uses for In Vitro Research

For several decades, transepithelial electrical resistance (TEER) measurement has become universally established as the most convenient, reliable and non-destructive method of evaluating and monitoring the growth of epithelial tissue culture in vitro. The confluence of the cellular monolayer is quickly determined by monitoring TEER. There is a gradual rise in TEER measurement as the gaps in the monolayer close. At confluence, the resistance plateaus and quits climbing. TEER measurement technology, first introduced to tissue and cell biologists by WPI in the mid 1980s has since been perfected and expanded to include a range of TEER related manual and automatic instrumentation.

Manual TEER Measurement

We offer both manual and automatic systems for making TEER measurements. The EVOM2 is the epithelial volt/ohm meter routinely used by tissue biology researchers to manually monitor the health of cellular monolayers. The EVOM2 comes with the chopstick style STX2 electrodes. For more repeatability, the STX100 series of electrodes are recommended. The EndOhm chambers were designed for endothelial measurements.

Automatic TEER Measurement System

Routine drug discovery studies, clinical trials and other cell research often requires a high throughput screening system for TEER measurements. The REMS automated robotic system is an excellent and affordable choice. The REMS works with 24 and 96 well cell culture plates from a variety of manufacturers.