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Blog
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March 16, 2023
World Precision Instruments' (WPI) legacy Robotic Epithelial Measurement System (REMS) and the new advanced, upgraded version of REMS, EVOM™ Auto, are high-throughput, automated transepithelial/transendothelial electrical resistance (TEER) measurement systems. These robotic systems, combined with EVOM™ technology, expedite TEER measurements.
A 96-well plate can be read within a few minutes using an automated TEER measurement system versus using a manual TEER measurement system, which can take up to 90 minutes to read a single 96-well plate. Manual systems require a user to move the electrode from one well to another and perform the rinsing in between, if needed. (Rinsing of the electrode while reading through a number of samples helps to prevent sample cross-contamination.) As automated systems measurements and rinsing are controlled by robotics, manual handling time is eliminated. Additionally, automated systems offer better measurement...more
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March 03, 2023
Have you got the new EVOM Auto TEER Measurement System for 96-well HTS plates? This short videos shows how easy it is to setup.
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March 03, 2023
Introduction
In the process of ‘cell cycle’, cells grow and divide into two genetically identical daughter cells. It is regulated by a complex signaling pathway which keeps cell homeostasis by regulating cell division and DNA duplication1. On the other hand, because cancer cells grow and divide indefinitely out of cell cycle control, anti-mitotic drugs are used to suppress abnormal proliferation...more -
March 01, 2023
Introduction
Cytotoxicity refers to the degree of damage to cells.
caused by chemical substances or physical factors. Measuring it through cytotoxicity assay is essential for drug development and biological research. Cells undergo complex signaling pathways that causes various cell death processes such as apoptosis, necrosis, and necroptosis. However, most cytotoxicity assays...more -
February 24, 2023
EVOM™ AutoLCI Automated Live Cell Imaging System
An integrated live cell monitoring system for stable imaging of suspension cells in immunological research
As white blood cells responsible for immune function are suspension cells that travel along blood vessels, immunology studies often use various suspension cell lines originating from white blood cells. Dealing with suspension cells, unlike adherent cells, slight movement of a plate when locating it on the microscope causes the cells to float. Aside from the problems caused by temperature and CO2 instability, it is in fact not possible to use a traditional microscope to monitor cells in real time. Therefore, in order to stably monitor suspension cells, a live cell imaging device such as EVOM™ AutoLCI that operates...more -
January 25, 2023
With You in mind, we just rolled out our redesigned website with some great features highlighted in this video! You get:
- One click menu for easy access to products
- Product filtering to quickly narrow down your product selection
- Simplified ordering lets you add products to your cart from any page with products listed
- Much more!
Our goal is to simplify your life. Let us know what you think of the new look and how we can help you find information faster...more
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January 25, 2023
The US FDA Modernization Act 2.0 replaces the 1938 Federal Food, Drug and Cosmetic Act which required animal testing prior to human trials. The new law, sponsored in the Senate by Rand Paul and co-sponsored by 11 other bi-partisan senators, eliminates that requirement. Representatives Vern Buchanan and Elaine Luria introduced the companion bill in the House, with over 105 bi-partisan cosponsors. President Biden signed the bill into law in December 2022. With the advent of modern research methods, we now have many options available to test the efficacy and safety of new pharmaceuticals without requiring the use of animals. Some of these methods include cell-based assays, microphysiological systems like organ-on-a chip (OOC), and bio-printed or computer models. In 2019, the cost of bringing a new drug to market varied greatly from $161...more
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September 13, 2022WPI is very excited to announce our newest product launch and collaboration with MatTek Life Sciences. The companies will offer both MatTek PermaCell Cell Culture Insert Plates and compatible customized World Precision Instruments’ STX HTS EVOM™ Electrode for TEER to their respective customers, available immediately to the life sciences market...more
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August 05, 2022
The ATC2000 is a low noise heating system for maintaining animal body temperature during expirimental procedures. Here we show you how to use the adaptive mode on the ATC2000 system.
- Press the Config button to access the configuration menu. Press the Config button again until the adaptive mode Enable displays.
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