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Laboratory Equipment Blog

  1. Versatile Microinjection Syringe Pump (UMP3T) for Injections in the Nanoliter to Milliliter Range
    May 15, 2020
    The UltraMicroPump3 is a versatile microinjection syringe pump designed to support the needs of a busy lab. The UMP3 Microinjector is suitable for delivery of media from nanoliters to milliliters. the UMP3 injecotor’s user interface and system design enables delivery of highly accurate and repeatable injections. The choice for thousands of scientists, it is widely cited in research papers.   Intuitive Touchscreen Display for Easy Setup The SMARTouch controller has an intuitive touch screen interface and an easy-to-use menu for quick configuration of the syringe size, volumes and f
  2. Why Choose an EVOM3 Over an EVOM2 for TEER Measurement
    May 15, 2020
    After 12 years, the next generation of the EVOM is born. Used for measuring Transepithelial Electrical Resistance (TEER) and monitoring the confluence of cell monolayers in culture well plates the EVOM3 TEER Measurement System enables researchers to carry out experiments more efficiently by improving the workflow, and increasing the stability and accuracy of readings over that of the EVOM2.  Here are six of the EVOM3 improvements.    
  3. 7 Reasons to Love the New EVOM3 for TEER Measurement
    May 15, 2020
    The NEW EVOM3 Epithelial Volt/Ohm Meter delivers improved workflow efficiency, increased stability and more repeatable measurements than traditional Trans Epithelial Electrical Resistance (TEER) meters. Here are seven things you will love about the new EVOM3.     1. It has an intuitive Touchscreen Display Providing users with vital feedback during experimental measurements, the EVOM3’s large touch screen offers a range of informational v
  4. Why Choose a Reusable Face Mask?
    April 23, 2020
    WPI offers the S9 self-priming respirator, a critical component of your personal protective equipment (PPE). The S9 is a reusable industrial face mask designed to KN95 standards. This means that it will block >95% of all particulate matter in the air larger than 2 µm in size. The face mask employs inexpensive replaceable filters. Looking at the initial cost, you may wonder if the resusable mask is worth the higher cost. This mask pays for itself very quickly when you consider how many disposable masks it replaces. Reuseable Face Mask Lasts Longer The long length of service of a WPI industrial reusable face mask (as opposed to disposable masks that use the same sort of filter material) is the result of its design. A plastic filter shield is securely
  5. Significance of Transepithelial/ Transendothelial Electrical Resistance (TEER) Measurement in Lung In vitro Models 
    April 13, 2020
      Epithelial and endothelial cells are known for their barrier function like selective permeability. Lung tissue is comprised of epithelial cellular layers, residing adjacent to endothelial layers and allowing exchange of oxygen and carbon dioxide between lung and blood. Currently, the biomedical research community’s major focus area is to understand the details of the infection caused by this novel coronavirus (2019-nCoV) or by similar viruses. This new virus can disrupt the lung’s normal cleaning ability to get rid of foreign particles in the lung, and the selective permeability or barrier function of the lung may become severely impaired. The adverse physiological effect may be sustained once the inflammatory cascade is initiated. Researchers in collaboration with clinicians are trying to develop vaccines and drugs to
  6. 8 Good Reasons to Choose the MICRO-ePUMP Microinjector for your Applications
    April 10, 2020
    Do you need a precision microinjector with an integrated pressure source for injections in the picoliter range? WPI’s new MICRO-ePUMP, which is comparable to the Ependorf Femtojet, is a portable solution for injecting DNA, RNA and proteins, as well as pre- and post- implantation in embryos. Whether you are doing disease modeling with zebrafish or viral research for SARS-CoV2, the MICRO-ePUMP has much to offer. Here are eight good reasons to choose the MICRO-ePUMP for your applications.   Convenient internal pressure source The convenient internal pressure source i
  7. Genetic Transfer (viral or non-viral vector) Using Microprocessor-Controlled Injector
    March 02, 2020
    With the first approved human gene therapy trial in 19891 (Rosenberg, et.al.), gene therapy has come a long way in modern medicine and is making inroads in clinics and the market in general.2,3 2017 was an important year for gene therapy when Luxurna, the first human gene therapy drug for an inherited retinal dystrophy, was approved by Food and Drug Administration (USA).4 Now several drugs are undergoing clinical trials. With an estimated $11 billion (USD) market in the next 10 years, both clinical trials and the pharmaceutical industry are expected to benefit immensely from gene therapy.5 With improved use of viral vectors (Adeno-associated virus (AAV), adenovirus, lentivirus, retrovirus, HSV) or non-viral vectors, research and clinical trials on the development of therapeutic genes have witnessed great
  8. Benefits of Nitric Oxide Detection using the WPI Free Radical Analyzer
    February 25, 2020
    Nitric oxide (NO) is an essential signaling molecule and is known to play a significant role in a multitude of physiological systems including the central nervous system (CNS), the cardiovascular system, the gastrointestinal tract, the immune system, and the renal system. 1-5 However, being highly reactive, detection and quantification of NO is very difficult.6,7 It requires a sensor that is sensitive, selective to NO, and easy to calibrate. WPI’s Free Radical Analyzer (4-channel TBR4100  and single-channel TBR1025) and the LabTrax Data Acquisition System with the o
  9. New Technology Makes Microinjection More Reliable, Repeatable and Affordable
    January 24, 2020
    Microinjection is the process of transferring genetic materials into a living cell using glass micropipettes or metal microinjection needles. Glass micropipettes can be of various sizes with tip diameters ranging from 0.1 to 10 µm. DNA or RNA is injected directly into the cell’s nucleus. Microinjection has been successfully used with large frog eggs, mammalian cells, mammalian embryos, plants and tissues. Microinjection has been expensive, can be a slow process and requires skilled personnel, but new technologies are making it even more reliable, repeatable and affordable. Pronuclear injection, inserting DNA or RNA into the nucleus of a fertilized oocyte to create transgenic organisms, lets researchers study the role of particular genes. This horizontal gene tr
  10. Advanced Flowcell Cleaning for Liquid Waveguide Capillary Cells
    December 20, 2019
    The purpose of this article is to describe a new cleaning procedure for thoroughly cleaning WPI flowcells, including Liquid Waveguide Capillary Cells (LWCCs), UltraPath flowcells and optical cuvettes. The image (right) shows a 3000 series LWCC with a MiniStar pump and the LWCC injection system placed on top of it. Preparation of Chemicals All chemical reagents should be of at least ACS-Grade, preferably HPLC-Grade. This procedure involves the use of caustic and flammable reagents. Consult the manufacturer’s MSDS for necessary safety precautions. Cleaning Solution #1: 0.5M Potassium Hydroxide in 100% Ethanol (e.g.: 7 g KOH in 250mL EtOH). After thoroughly mixing, filter the solution through a 20µm pore size filter. Cleaning Solution #2
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