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Laboratory Equipment Articles

  1. Many Modules for Cell/Muscle Testers
    April 24, 2013
    WPI offers several muscle tester platforms, including the: SI-CTS200 –Cell Tester for experiments on single cells and small muscle tissues SI-HTB – Horizontal Tissue Bath Plaftorm These systems include a Signal Conditioning Amplifier System which is the electronic component of the system. It is configured for a researchers individual needs and comes with the modules a researcher chooses. The amplifier system can accommodate up to eight channels. Current available SI-H modules include:
  2. EVOM or Volt Meter: Defining the Difference
    April 24, 2013
    A Volt Meter A volt-ohm meter may apply a constant voltage of unknown current across the membrane and damage the cells electrically and also leave a chemicalimbalance in the electrodes. WPI experimented with two volt-ohm meters: An expensive Fluke meter applies a DC voltage of 50 to 80mV, which (in a 1000Ω membrane) will pass 80µA. With a 200Ω membrane, this is 400µA. A discount meter puts out 500mV DC, which will pass 500µA through the membrane. With a 200Ω membrane, this is 2.5mA. Volt Meter Charges or Electrocutes Cells When you use a volt ohm meter to test a cell layer, the Ag/AgCl electrodes accumulate an unbalanced chemical charge. If the cells are not electrocuted in the process, they also accumulate a charge. The unbalanced electrodes can now act as a source of voltage and current that has to be ov
  3. Neuroscience Cannulas for in vivo Investigation of Rodents
    April 24, 2013
    The WPI cannula system for neuroscience study and pre-clinical research includes an entire range of cannula options. You are guaranteed: Exceptional Quality Best Prices Rapid Order Response The three primary components include the Guide Cannula, the Internal Cannula and the Dummy Cannula (cap). WPI cannulas are beveled inside and out and then polished to remove any burrs and ensure that the inside diameter is
  4. SI-H Cell Tester Opens a New Window to Cellular Studies
    April 24, 2013
    New technologies developed by SI-H offer incredible opportunities for muscle physiology researchers. Up until now, many studies required an entire day to perform a single trial. Now, after isolating the cells, these same studies can be run on single cells in a matter of minutes. Because we are working on single cells, we can test living organisms. Tetanus, cardiac work loops, afterload and constant load contraction studies, calcium imaging, sarcomere spacing, NAD/NADH and FAD/FADH studies can all be performed on a single cell with the SI-H CTS200 Cell Tester system. According to Dr. Harm Knot (staff muscle physiologist), “The new Cell Tester, a novel cell biology research tool, is set to revolutionize the emerging field of
  5. Selecting the Correct Tip for Your NanoFil Microinjection Application
    April 24, 2013
    Specially designed tips as small as 36 gauge (110 micron OD) are offered in both blunt and beveled styles. Our studies have shown that these tips will cause less trauma to the tissue than any other form of micro syringe currently in use. NanoFil has a unique coupling mechanism that allows many different forms of small tubing and tips to be coupled with the syringe barrel. Configurations Based on application requirements, NanoFil can be used in several different configurations. Direct Microinjection by Hand This is the simplest and most economical way to inject. Any of our tips can be inserted directly into the NanoFil
  6. EVOM2-How to Equilibrate Your STX2
    April 24, 2013
    The World Precision Instruments (WPI) EVOM2 is used for making trans epithelial electrical resistance (or TEER) measurements. Two silver/silver chloride pellets are used for the electrodes. The chloride ion tends to migrate, which is a reversible reaction. But, because of this chloride ion swapping, the electrodes need to be polarized before each use. Before using the meter for making voltage measurements, equilibrate the electrodes. This video shows you how.   More Info
  7. Microsquisher at Work with Stem Cell Aggregates
    April 24, 2013
    The following video shows how Dr. Todd McDevitt's laboratory at Georgia Tech is using the CellScale Microsquisher on stem cell aggregates. The MicroSquisher is designed to perform compression testing on specimens between 50µm and 2mm with force resolutions as small as 50nN. Forces are determined from the deflection of a flexible cantilever beam to which one compression plate is attached. Displacement control is achieved by manipulating the base of that beam using a motorized piezo stage.      More Info WPI is the exclusive North American distributor for Cell Scale. For more information, email us at
  8. How To Test Your EVOM2 Meter
    April 24, 2013
    The World Precision Instruments (WPI) EVOM2is used for making trans epithelial electrical resistance (or TEER) measurements. We recommend that you test your EVOM2 before you use it for the first time and then periodically after that. If there is a concern that the meter or the electrode is not functioning properly, test the meter first. This video shows how to test the meter. More Info
  9. How to Fill a 2 mm Sensor Sleeve with Filling Solution
    April 24, 2013
    In this video, Nikki demonstrates how to prepare and fill a 2mm biosensor and prepare to calibrate an ISO-OXY-2 oxygen sensor.   More Info
  10. How to Calibrate an ISO-HPO100
    April 24, 2013
    In this video, WPI Chemist Nikki Scafa demonstrates how to calibrate the WPI ISO-HPO100 hydrogen peroxide microsensor.  More Info
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