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Product Information
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July 27, 2023
WPI’s EVOM™ Technology is a well-established, non-invasive method to verify tissue integrity or barrier function, confluence, and tissue properties in 2-D and 3-D formats. To get the best TEER measurement results with WPI’s EVOM technology, you need to select suitable electrodes based on your application.
Here are some criteria to consider when selecting a TEER measurement electrode...more
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July 24, 2023
In 2022, the United States Food and Drug Administration (FDA) approved 37 new drugs, of which 20 were chemical entities and 17 were biologics. In 2023, drug discovery remains strong with many new advancements a result of changing landscapes in both the types of drugs that are being developed and the new and innovative assay that are being launched to evaluate drugs preclinically. Therapeutic development is still highly focused on diseases that affect large populations of people for which there are lack of effective treatments, with 2023’s most anticipated drug launches expected to be in areas of cancer, Alzheimer’s disease, cardiovascular disease, and ulcerative colitis...more
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July 19, 2023
In 2022, the United States Food and Drug Administration (FDA) approved 37 new drugs, of which 20 were chemical entities and 17 were biologics. In 2023, drug discovery remains strong with many new advancements a result of changing landscapes in both the types of drugs that are being developed and the new and innovative assay that are being launched to evaluate drugs preclinically. Therapeutic development is still highly focused on diseases that affect large populations of people for which there are lack of effective treatments, with 2023’s most anticipated drug launches expected to be in areas of cancer, Alzheimer’s disease, cardiovascular disease, and ulcerative colitis...more
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July 06, 2023
Choosing a dependable lab equipment supplier is crucial for ensuring the quality, reliability, and timely delivery of the equipment you require. When your research is on the line, you need a company you trust, a supplier with a proven track record and a service team to back you up. Here are a few important considerations when selecting a lab equipment supplier...more
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July 05, 2023
In any laboratory, having key lab supplies is almost as important as having the major equipment. Choosing a reputable supplier of these necessary supplies is as important as having quality laboratory supplies when you need them. WPI wants to be your partner in early drug discovery, and we stock a wide variety of lab supplies, many of which can ship the same business day. Having a variety of lab supplies ready to ship makes us a dependable research partner. Here are some of the popular supplies that we keep on hand to meet your needs for your upcoming experiment...more
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June 30, 2023
In any laboratory, having key lab supplies is almost as important as having the major equipment. Choosing a reputable supplier of these necessary supplies is as important as having quality laboratory supplies when you need them. WPI wants to be your partner in early drug discovery, and we stock a wide variety of lab supplies, many of which can ship the same business day. Having a variety of lab supplies ready to ship makes us a dependable research partner. Here are some of the popular supplies that we keep on hand to meet your needs for your upcoming experiment...more
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June 16, 2023
The adhesive you select will depend largely on your biomedical research laboratory application. If you are building electrodes, you might use a silver-filled, conductive epoxy to connect a Ag/AgCl pellet. For instantaneous bonding when mounting a rodent brain slice, you might select an ethyl cyanoacrylate. When you are looking for a low toxicity adhesive with some elasticity and good moisture resistance, a silicone adhesive is the option of choice. When used with living tissue, an adhesive must be:...more
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June 06, 2023
This article shows you how to appropriately care for your surgical insturments to ensure long lasting, highly functioning tools for your application...more
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June 05, 2023
Cyanoacrylate adhesives have been on the market since 1958. Most industrial or household grade cyanoacrylate (like Super Glue) are made of shorter alkyl chain derivatives such as methyl or ethyl cyanoacrylate (WPI #7341 and #7342). They are very useful for temporarily holding tissues such as mounting specimens for microtome sectioning. A family of adhesives containing octyl cyanoacrylate, a plasticizer and stabilizer, was developed In the 1990's (one of them approved by FDA for human use). When bonding to tissue, these new adhesives are four times stronger and less toxic than butyl cyanoacrylate. Compared with the traditional suture, the new super adhesive has several advantages. Cyanoacrylates Not Suitable for Live Animals...more
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May 25, 2023
If the EVOM™ Auto software switches from Resistance to TEER mode while you are selecting menu options, here's a quick tip:
Be careful when selecting Resistance mode, do not tap the background window and do not click on the side arrows.
Tapping the background window will switch you to TEER mode.
Instead, tap an option on the forefront square window to stay in Resistance mode...more
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May 02, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows details the features and functions of the Experiment window on the EVOM™ Auto:
After you have defined a sequence, you can begin running an experiment.
The Experiment window shows a representation of the plate on the left side of the window.
On the right side of the window, you see these...more
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April 27, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to schedule an operation on the EVOM™ Auto:
The data acquisition functions of the EVOM™ Auto may be repeated at a defined time interval when multiple scans of a plate are needed. The scheduled operations are displayed on the right side of the Experiment window in the Current State area. The control buttons for scheduling...more
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April 25, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to stabilize the electrode array on the EVOM™ Auto:
First, select Maintenance on the main menu. To stabilize, press the + or - buttons to set the timer to the desired time in minutes in the stablize frame.
Next, Select the radio button for the rinse station containing the buffer solution. Then, fill the appropriate rinse station with the buffer solution...more
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April 20, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to chloride the electrode array on the EVOM™ Auto:
To chloride the electrode array, select Maintenance on the main menu.
Four control buttons are located at the bottom of this window:
- Go Home- Positions the electrode array in the home position.
- Calibrate- Calibrates the sensor head using the internal...more
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April 18, 2023
The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.
The video below shows you how to create a plate file on the EVOM™ Auto:
1. To Create a measurement sequence, select the Manage Sequence menu from the Home screen. A list of the existing sequences displays, and you may open and edit any existing sequence or select New Sequence to create a new one. If you select New Sequence, a popup allows you to...more