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Product Information
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February 11, 2019
Not all fibers are created equal. When your research is on the line, the choice is clear. Because,WPI optical fibers are qualified for your next project.
Think of it this way–it is optical fiber that finally addresses the lingering issue of fiber performance variability. Qualified fiber ensures repeatability from one fiber cable to the next. Let me explain. Other attributes of a complete -
February 08, 2019
Trusted Partner for Reliable Measurements
WPI is dedicated to being your preferred OEM supplier for optical fiber products by offering the following:
- Quality Products and Expert Service – After over 50 years in business, we’ve learned that it takes more to be your partner than just great quality and fair prices. We have implemented measures such as our ISO-9001:2015 certification throughout our home office and production facility to improve our efficiency and ensure quality. We also have invested in six sigma certifications with continuing effort to improve processes within the organization.
- Personal Service – A dedicated OEM account manager and a seasoned optical engineering team with over 20 years of technical design experience make all the difference for our customers.
- Cost Effective Solutions – Quality optical fiber products...more
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November 28, 2018
Selection of Electrodes for TEER Measurements
Transepithelial electrical resistance (TEER), also referred as the transepithelial resistance (TER) is used to monitor cellular health. TEER is comprised of measurements of the transcellular pathway (i.e., resistance due to an individual cell) and paracellular pathway (i.e., resistance due to the formation of the cellular junctions). TEER is commonly used to monitor cellular confluence. TEER values can indicate changes in the cellular monolayer permeability, showing the monolayer barrier function of cells such as, endothelial (brain microvessel) and epithelial (alveolar, kidney, and intestinal) cells. High TEER values generally reflect tighter cellular monolayers or cellular junctions (Lewis 1996, Matter and Balda 2003, Denker and Sabath 2011). A few major benefits of WPI TEER measurement systems are described below. The TEER values (electrophysiological analysis) can be combined with other analysis methods to further understand...more
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October 08, 2018
Measuring CDOM with a Fiber Optic Liquid Waveguide Capillary Cell
One's imagination is the limit with practical uses of WPI's Liquid Wavelength Capillary Cells(LWCC), also referred to in the fiber optic spectroscopy community as a Long Pathlength Flow Cell. This fiber optic sampling accessory for absorbance measurements combines increased optical pathlengths with small sample volumes making them ideal for water analysis such as CDOM.
Two optical fibers couple to this sampling accessory one to send light to the sample cell and the second to send light to a spectrometer. The length of the fiber optic cable can vary allowing investigators to either spot test CDOM in the lab from collected water samples or continuously monitor CDOM of a body of water under investigation with this sampling accessory coupled to a fiber optic spectrometer and...more
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August 22, 2018
Clean, Consistent Cut Every Time
When you need to quickly take minimally invasive, small samples, the biopsy punch is an easy choice. The biopsy punch is a hand held, pencil-shaped instrument with a slender, pencil-like body. It is lightweight with a hollow, circular, stainless steel, cutting tip.
In 1887 Edward Lawrence Keyes, the first president of the American Association of Genitourinary Surgeons, was the first doctor who documented the importance of using the biopsy punch for dermatological diagnostics. He observed that the skin tissue samples can be obtained without complications, minimal bleeding and no need for suturing.
Uses for Biopsy Punches
Punches are not solely used in dermatology. Biopsy punches are also designed for therapeutics, cosmetic...more
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July 16, 2018
This 900A video series of 6 videos is designed to help familiarize you with the basic operation of the 900A Micropressure System. The 900A was designed for measuring pressures in kidney tubules, and it has many applications. It has recently been used for measuring...more -
March 13, 2018
When you are selecting surgical instruments for a procedure, here are a few key points to consider - What procedure are you performing? Published research papers usually indicate which instruments other researchers have used for similar procedures. The correct surgical instrument for a particular procedure makes a difference on the outcome of that technique.
- What is the size of your subject? An instrument that is perfect for a 200–300 g rat (about 22–25 cm long) may not be the best choice for a neo-natal mouse of about 15 g (about 1–2.5 cm long).
- How often will the instrument be used? If you perform more than 100 cuts per day, a pair of titanium scissors or a pair of scissors with tungsten carbide inserts would be worth considering. They stay sharp longer.
In this article we will consider some of...more
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February 13, 2018
In this video you'll see how to replace the gasket in a Nanoliter2010.
If you have questions, contact us at 866.606.1974 (US Toll Free) or at [email protected]. To request a formal quote, please email us at [email protected].
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June 27, 2017
Absorption of light correlates to the energy of a photon that is taken-up by electrons of the substance atom. The electromagnetic energy is transformed into internal energy of the absorbent substance. The absorbance of a substance quantifies how much of the incident light is absorbed by it (instead of being reflected or refracted). Precise measurements of the absorbance at many wavelengths allow the identification of a substance via absorption spectroscopy, where a sample is illuminated from one side, and the intensity of the light that exits from the sample in every direction is measured (see Fig. 1). A few examples of absorption are ultraviolet–visible (UV-Vis) spectroscopy or infrared (IR) spectroscopy....more
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June 27, 2017
The use of fluorescent probes in cell physiology has emerged as indispensable tool in the analysis of cell functioning over recent years. The physics underlying fluorescence is illustrated by the electronic-state diagram (so-called Jablonski diagram, see Fig. 1), showing the three-stage process to create the fluorescent signal (Excitation - Excited/State Lifetime - Fluorescence Emission) in a fluorophore/indicator and simplified described below.
Fig. 1– Jablonski diagram illustrating the processes of fluorescence by absorption of higher photon energy by a fluorophore and subsequent emission of lower photon energy, resulting in fluorescence during the fluorescence-lifetime.
Fluorescence...more
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November 20, 2015
For small batches of cell culture
Are you ready to perform experiments involving a cultured cell monolayer? If your monolayer has not reached confluence, you may have holes or gaps in the monolayer that would prevent collection of valid experimental data. When confluence is reached, the electrical resistance across the monolayer peaks and then plateaus. The EVOM2 meter was designed specifically for this application.
The EVOM2 is the ideal meter for use when you are making manual TEER measurements on small batches of cell cultures and do not require a high throughput system.
EVOM2 - Perfect for TEER
The EVOM2 was designed to measure TEER resistance without damaging the epithelial cells. It passes a constant current of low amperage...more
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October 20, 2015
LabTrax 8/16 hardware combined with MDAC software is an excellent choice for WPI's SI-H line of muscle physiology products like the SI-MT Muscle Platform, SI-CTS Cell Tester and SI-HTB Horizontal Tissue Baths. This data acquisition system is ideal for testing physiological characteristics like the contractile and elastic properties of different tissues in various conditions like isometric, anisometric or isotonic states. This data acquisition system was designed with the muscle researcher in mind, because the knowledge of physiological characteristics of muscles is critical when quantifying the beneficial or adverse effects of a stimulus (like a pharmaceutical drug) on muscle function in pre-clinical studies.
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October 04, 2015
The type of pump you choose for your fluid handling will largely depend on your laboratory application. In this article, we will compare the popular pump types.
Microinjectors
WPI Microinjectors use carefully regulated air pressure for injecting cells with fluid. Injected volumes range from picoliters to nanoliters. The port supplies positive pressure for high-pressure ejection. The pressure port maintains a low positive “compensation” pressure to the injecting pipette between injection pulses to prevent fluid uptake through...more
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June 25, 2015Application kits are specially designed for eye research for injecting retinal pigment epithelium (RPE) and for intraocular (IO) injections. In addition, these kits may be used for brain injection in mice. They need to be used...moreJune 19, 2015
The proper care and handling of your valuable surgical instruments will improve their longevity and function. Choose a protocol appropriate for your environment from the cleaning techniques below. See the videos here.
RINSING
Immediately after use, rinse instruments under warm or cool running water to remove all blood, body fluids and tissue. Dried soils may damage the instrument surface and make cleaning very difficult. Do not use hot water as this will coagulate proteinous substances.
CLEANING TECHNIQUES
Time, temperature, and agitation play important roles in the cleaning process.
Time — the efficiency of cleaning chemicals is often time dependant
Temperature — higher temperature cleaning solutions result in better cleaning...more
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