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EndOhm
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November 28, 2018
Selection of Electrodes for TEER Measurements
Transepithelial electrical resistance (TEER), also referred as the transepithelial resistance (TER) is used to monitor cellular health. TEER is comprised of measurements of the transcellular pathway (i.e., resistance due to an individual cell) and paracellular pathway (i.e., resistance due to the formation of the cellular junctions). TEER is commonly used to monitor cellular confluence. TEER values can indicate changes in the cellular monolayer permeability, showing the monolayer barrier function of cells such as, endothelial (brain microvessel) and epithelial (alveolar, kidney, and intestinal) cells. High TEER values generally reflect tighter cellular monolayers or cellular junctions (Lewis 1996, Matter and Balda 2003, Denker and Sabath 2011). A few major benefits of WPI TEER measurement systems are described below. The TEER values (electrophysiological analysis) can be combined with other analysis methods to further understand...more
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February 02, 2015
Here are some frequently asked questions (FAQ) about TEER measurement using an EVOM2.
- Are the electrical resistance and transepithelial electrical resistance (TEER) the same thing?
- What is an EndOhm chamber?
- How is an EVOM2 used for measuring confluence?
- Why use an EndOhm instead of a STX?
- How do I clean my electrode?
- What about electrode preconditioning?
- Can you give me a simple data acquisition system for TEER?
- What are the TEER measurement challenges that I may encounter?
- Can you suggest some experimental...more
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September 03, 2013
The EVOM2 measures trans epithelial electrical resistance (TEER) in tissue culture research. The EndOhm series of chambers for the EVOM2 are designed to accurately measure trans endothelial electrical resistance. Learn how to setup your EndOhm Chamber with an EVOM2 Epithelial Volt Ohm Meter. See how to equilibrate the sensors when taking a voltage measurement. And, learn how to take resistance and voltage measurements.