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Laboratory Equipment Blog

  1. INs and OUTs of Surgical Needles for Suturing
    April 24, 2013
    Surgical needles are specifically designed for their application. The diagram below shows the difference between cutting edge and taper point needles. Cutting edge needles have sharp edges that penetrate easily through tough tissue. They are ideal for suturing skin and dense dermal tissue.    Taper point needles pierce and spread tissue without cutting it. They are ideal for suturing delicate, soft tissue when minimal trauma is desired.
  2. SI-H Cell Tester Opens a New Window to Cellular Studies
    April 24, 2013
    New technologies developed by SI-H offer incredible opportunities for muscle physiology researchers. Up until now, many studies required an entire day to perform a single trial. Now, after isolating the cells, these same studies can be run on single cells in a matter of minutes. Because we are working on single cells, we can test living organisms. Tetanus, cardiac work loops, afterload and constant load contraction studies, calcium imaging, sarcomere spacing, NAD/NADH and FAD/FADH studies can all be performed on a single cell with the SI-H CTS200 Cell Tester system. According to Dr. Harm Knot (staff muscle physiologist), “The new Cell Tester, a novel cell biology research tool, is set to revolutionize the emerging field of
  3. Neuroscience Cannulas for in vivo Investigation of Rodents
    April 24, 2013
    The WPI cannula system for neuroscience study and pre-clinical research includes an entire range of cannula options. You are guaranteed: Exceptional Quality Best Prices Rapid Order Response The three primary components include the Guide Cannula, the Internal Cannula and the Dummy Cannula (cap). WPI cannulas are beveled inside and out and then polished to remove any burrs and ensure that the inside diameter is
  4. EVOM or Volt Meter: Defining the Difference
    April 24, 2013
    A Volt Meter A volt-ohm meter may apply a constant voltage of unknown current across the membrane and damage the cells electrically and also leave a chemicalimbalance in the electrodes. WPI experimented with two volt-ohm meters: An expensive Fluke meter applies a DC voltage of 50 to 80mV, which (in a 1000Ω membrane) will pass 80µA. With a 200Ω membrane, this is 400µA. A discount meter puts out 500mV DC, which will pass 500µA through the membrane. With a 200Ω membrane, this is 2.5mA. Volt Meter Charges or Electrocutes Cells When you use a volt ohm meter to test a cell layer, the Ag/AgCl electrodes accumulate an unbalanced chemical charge. If the cells are not electrocuted in the process, they also accumulate a charge. The unbalanced electrodes can now act as a source of voltage and current that has to be ov
  5. Many Modules for Cell/Muscle Testers
    April 24, 2013
    WPI offers several muscle tester platforms, including the: SI-CTS200 –Cell Tester for experiments on single cells and small muscle tissues SI-HTB – Horizontal Tissue Bath Plaftorm These systems include a Signal Conditioning Amplifier System which is the electronic component of the system. It is configured for a researchers individual needs and comes with the modules a researcher chooses. The amplifier system can accommodate up to eight channels. Current available SI-H modules include:
  6. Exploring the Intracellular World
    April 24, 2013
    Contributing Author: Dr. Steve Andre (Muscle Physiologist) All living cells maintain a difference in electrical charge between the solutions that are inside and outside the cell membranes. The voltage difference across the cell membrane is usually at a steady level known as the resting membrane potential. The resting membrane potentialis produced by the differential distribution of ions on either side of the membrane. In muscle fibers, the potassium concentration inside the cell is over 50 times greater than the ion’s concentration in the extra­cellular fluid. On the other hand, the concentration of sodium is 10 times greater outside the membrane than inside. The concentration gradient of potassium is greater and in the opposite direction to the sodium concentration gradient. The ion concentrations are governed by three factors: Sodium-potassium pu
  7. Muscle Physiology Basics
    April 24, 2013
    Cellular Organization When building any structure, whether it’s a bridge or a protein, three elements are required: Building materials Energy Building plans The same is true in biological systems: Proteins are the structural material used for building. They provide the shape and substance of cells, tissues, organs and living matter. Carbohydrates are converted to energy to fuel the cellular building process. If more energy is available than is required for a project, the carbohydrates are converted to fats for long term energy storage. Finally, nucleotides within the nucleus of a cell provide the blueprints for the project. A Cell – Simplified
  8. Taper Surgical Needles for Delicate Suturing
    April 24, 2013
    Taper point surgical needles pierce and spread tissue without cutting it. They are ideal for suturing delicate, soft tissue when minimal trauma is desired. Eye Needles, 5/16 of a Circle Taper point, 5/16 Circle  501962 Size 00 11mm pack of 12  501963
  9. Choosing a Cuvette: Optical Glass or Quartz
    July 12, 2011
    Synthetic quartz can be used in deep UV applications and is recommended for fluorescent applications, as it does not exhibit background fluorescence. Quartz cuvettes (absorbance, fluorescence and flow) are shipped individually packaged, glass cuvettes are shipped in packages of 10 cuvettes.
  10. WPI Acquires the Muscle Physiology Experts SI-H
    March 26, 2009
    Late in March, WPI sealed the deal making Scientific Instruments-Heidelberg a part of the WPI family of companies. SI-H is the leader in muscle physiology research equipment. Designing quality equipment since 1988, SI-H focuses on the investigation of intact and chemically skinned muscle preparations, as well as the investigation of single cells.
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