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March 13, 2018When you are selecting surgical instruments for a procedure, here are a few key points to consider What procedure are you performing? Published research papers usually indicate which instruments other researchers have used for similar procedures. The correct surgical instrument for a particular procedure makes a difference on the outcome of that technique. What is the size of your subject? An instrument that is perfect for a 200–300 g rat (about 22–25 cm long) may not be the best choice for a neo-natal mouse of about 15 g (about 1–2.5 cm long). How often will the instrument be used? If you perform more than 100 cuts per day, a pair of titanium scissors or a pair of scissors with tungsten carbide inserts would be worth considering. They stay sharp longer. -
February 13, 2018In this video you'll see how to replace the gasket in a Nanoliter2010. More Info If you have questions, contact us at 866.606.1974 (US Toll Free) or at wpi@wpiinc.com. To request a formal quote, please email us at quotes@wpiinc.com. -
June 27, 2017Absorption of light correlates to the energy of a photon that is taken-up by electrons of the substance atom. The electromagnetic energy is transformed into internal energy of the absorbent substance. The absorbance of a substance quantifies how much of the incident light is absorbed by it (instead of being reflected or refracted). Precise measurements of the absorbance at many wavelengths allow the identification of a substance via absorption spectroscopy, where a sample is illuminated from one side, and the intensity of the light that exits from the sample in every direction is measured (see Fig. 1). A few examples of absorption are ultraviolet–visible (UV-Vis) spectroscopy or infrared (IR) spectroscopy. -
June 27, 2017The use of fluorescence for sensing and imaging of the cellular signaling pathways has emerged as an indispensable tool in modern physiology, providing dynamic information of quantity and localization of the molecules of interest. Using appropriate indicator dyes, molecules alter their fluorescent characteristics in response to ion binding or membrane integration, so that the optical signal from the indicator can be measured to monitor the amplitude and the time course of various metal ions like Na+, K+, Mg2+ and Ca2+, as well as pH and membrane potential, in cellular compartments. A specific target molecule like Ca2+ is responsible for many physiological functions, such as neurotransmitter release, fertilization and ion channel functions. Studying the cellular channel functions is directly related to the transient increase in the myoplasmic free calcium concentration (Δ[Ca2+ -
June 27, 2017Absorption of light correlates to the energy of a photon that is taken-up by electrons of the substance atom. The electromagnetic energy is transformed into internal energy of the absorbent substance. The absorbance of a substance quantifies how much of the incident light is absorbed by it (instead of being reflected or refracted). Precise measurements of the absorbance at many wavelengths allow the identification of a substance via absorption spectroscopy, where a sample is illuminated from one side, and the intensity of the light that exits from the sample in every direction is measured (see Fig. 1). A few examples of absorption are ultraviolet–visible (UV-Vis) spectroscopy or infrared (IR) spectroscopy. Fig 1. Concept of absorbance spectroscopy using white light and o
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June 27, 2017The use of fluorescent probes in cell physiology has emerged as indispensable tool in the analysis of cell functioning over recent years. The physics underlying fluorescence is illustrated by the electronic-state diagram (so-called Jablonski diagram, see Fig. 1), showing the three-stage process to create the fluorescent signal (Excitation - Excited/State Lifetime - Fluorescence Emission) in a fluorophore/indicator and simplified described below. Fig. 1– Jablonski diagram illustrating the processes of fluorescence by absorption of higher photon energy by a fluorophore and subsequent emission of lower photon energy, resulting i -
June 09, 2017The notable expert in the area of electrochemical sensors, Xueji Zhang, PhD, Sr. Vice President and Chief Scientist at WPI, is leading the development for microsensors (including the ISO-H2S-100-Cxx) for free... -
April 14, 2017World Precision Instruments was selected to receive the FVMA (Florida Veterinary Medical Association) Industry Award for 2017. -
February 10, 2016When precision and repeatability of motion are critical, WPI's MTM-3 Motorized Stereotaxic Frame outperforms manual stereotaxic frame models, and it greatly reduces human error. The motorized axis of the MTM-3 provide precise, controlled, 3-dimensional placement of any probe or accessory within the working space of a stereotaxic frame. No computer is required. The MTM-3 supplied with WPI stereotaxic frames is also compatible with standard stereotaxic frames and may be adapted to existing frames of other manufacturers. Dual manipulator arm motorized systems are also available. MTM-3 Stereotaxic Frame Introduction This videos gives a 2 minute overview of the new frame. Why Get the MTM-3 Stereotaxic Frame for your Laboratory? For more inf -
November 20, 2015For small batches of cell culture Are you ready to perform experiments involving a cultured cell monolayer? If your monolayer has not reached confluence, you may have holes or gaps in the monolayer that would prevent collection of valid experimental data. When confluence is reached, the electrical resistance across the monolayer peaks and then plateaus. The EVOM2 meter was designed specifically for this application. The EVOM2 is the ideal meter for use when you are making manual TEER measurements on small batches of cell cultures and do not require a high throughput system. EVOM2 - Perfect for TEER The EVOM2 was designed to measure TEER resistance without damaging the epithelial cells. It passes a constant curre