STX 100 Series Electrodes
New electrode for High Throughput Screening (HTS) protocol cell culture inserts
STX 100 C and STX 100 F

Designed for 24-well HTS plate (Corning Costar and BD Falcon) and with 96-well plates (Millipore)

Improved accuracy down to 5 Ohm

Sterilized with EtO, alcohol or bactericide

Although the STX100 was developed to meet the demand of the pharmaceutical industry's HTS protocols, it is also a very useful tool for general TEER research where precision, reproducibility, less disturbance to the cell and minimal contamination is required during TEER measurement. The STX100 is ideal for applications requiring qualitative analysis of TEER over long-term experimental conditions.


EVOMX is a modified version of the EVOM and is recommended for use with STX100. Its measurement switch and circuits have been modified to remain ON continuously. This enables the user to have one hand free to move the electrode while using the other to note the readings. A BNC recorder output connector is provided on the EVOMX to permit direct recording of TEER measurements to a chart recorder or computer-based data-acquisition system.; With the development of a High Throughput Screening (HTS) protocol for faster drug discovery, a new line of cell culture filter plates have been introduced by several major cell culture insert manufacturers. These HTS plates normally have either 24 or 96 individual cell culture inserts bonded together as one plate so that it can be handled by a robot apparatus. In response to these developments, WPI has developed an automatic REMS system and a manual electrode, STX100, for TEER measurements using HTS plates.

STX100's design is based on the same reliable design principle as the universally used STX2 electrode, with several important modifications. The size of the electrode tip has been reduced to 1.5 mm to facilitate positioning through the narrower slit of the HTS plate. The STX100 electrode itself is constructed using a stronger material for higher durability and maximum usage applications. The bottom section of the electrode is shaped to fit neatly into the keyhole shaped filter well. This enables the STX100 electrode to produce increased accuracy and reproducibility of TEER readings (+- 5W) compared to the standard STX2. Three versions of STX100 are available, designed to fit the Corning Costar HTS plate and the Millipore Multiscreen CaCo 96 well plate. Measurement can be directly performed when the HTS plate is in either a common or divided tray, reducing the possibility of contamination as well as mechanical damage to the cultured cells.


STX 100 M

STX100C STX100 for Corning Costar HTS Transwell-24
STX100F STX100 for Falcon HTS Multiwell Insert System 24 Well Plate
STX100M STX100 for Millipore MultiscreenTM CaCo 96 Well Plate
STX100C96 STX100 for Corning HTS 96 Well Plate
Data Acquisition System and Accessories
LabTrax™ Data Recording System
2851 Standard BNC Cable, 6 ft (1.8m)
500184 Standard BNC Cable, 10 ft (3m)