Trans Epithelial Electric Resistance (TEER) Measurements

EVOM™ Epithelial Voltohmmeter
The EVOM was the first instrument designed specifically to perform routine TEER (Trans Epithelial Electric Resistance) measurement in tissue culture research. The battery-powered EVOM produces an AC current that avoids adverse effects on tissues, which can otherwise be caused, by a DC current — including electrode metal deposits. The EVOM has an easy-to-read LC display and is also available with a BNC recorder output (EVOMX). Input impedance of the EVOM is greater than 1010 ohm, and resistance ranges from 0 to 1999 ohm; and 0 to 20,000 ohm can be monitored using the switchable range setting located on the instrument front panel.
During the last two decades TEER measurements have become universally established as the most convenient, reliable and non-destructive method to evaluate and monitor the growth of epithelial tissue cultures in vitro. The confluence of the cellular monolayer is quickly determined by a sharp increase in TEER. Recently there has been a significant surge of interest in introducing a combined electrode for resistance measurements in the Millipore 96-well PAMPA (parallel artificial membrane permeability assay) plate.
TEER measurement technology, which was first introduced by WPI in the mid-1980’s, has since been perfected and expanded to include a range of TEER related manual and automatic instrumentation.
Manual
References
Specifications
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EVOM Epithelial Tissue Voltohmmeter (includes STX2 electrode set)
REPLACEMENTS AND ACCESSORIES
STX2 Replacement “Chopstick” Electrode Set
STX3 Adjustable Tip Spread “Chopstick” Electrode Set
3993 Electrode Adapter (for electrodes with 2 mm pins)
13685 Modular Cable, 7 ft
L200E-1 One Channel Economy Recorder, 200mm
13347 13347 Chart Recorder Adapter
2851 Standard BNC Cable, 6 ft (1.8m)
500184 Standard BNC Cable, 10 ft (3m)