DVC-1000 Two-Channel Voltage / Current Clamp
WPI's DVC-1000 is well-known and widely used for studying epithelial tissues. Each DVC-1000 consists of two separate clamp instruments -- One for clamping a control tissue, another for clamping a test tissue. This dual clamp technique lets you monitor changes in membrane permeability as a function of voltage or applied chemical agents.

Either clamp unit operates in five modes. Voltage clamp: Clamps the tissue voltage to a given level and displays the current required to maintain that level. Amplify: Shows the potential difference between the two voltage electrodes. Current clamp: Lets you deliver a constant current between the two current electrodes while simultaneously monitoring voltage changes at the tissue.

Timer: Functions in either current clamp or voltage clamp experiments, letting you cycle automatically between zero clamp and a preset clamp level. Remote: Allows you to control clamp operation from a computer or other logic level source.

Small preamplifiers (included) which mount close to the chamber let you connect to voltage and current electrodes without long cables or agar bridges. DVC-1000 also features a unique ±100 V power supply capable of delivering up to 1 mA of clamp current. Each clamp lets you correct for input offset voltages and fluid resistance error.


References

DVC-1000 SPECIFICATIONS
PROBES
INPUT IMPEDANCE
1012 Ohms
LEAKAGE CURRENT
100 pA max
MAXIMUM INPUT VOLTAGE
10 V
VOLTAGE CLAMP
CLAMP VOLTAGE RANGE:
SET CLAMP POT
±100 mV
EXTERNAL COMMAND
±1 V
COMMAND FACTOR
10 mV/mV
MAX. CLAMP CURRENT
±1 mA
CURRENT CLAMP
 CLAMP CURRENT RANGE:
SET CLAMP POT
±1 mA
EXTERNAL COMMAND
±1 mA
COMMAND FACTOR
1 mV/µA
COMPLIANCE
±100 V
INPUT OFFSET RANGE ±130 mV
FLUID RESISTANCE
COMPENSATION RANGE
0-1000 Ohms
TEST CURRENT 10 µA adjustable
OUTPUT RESISTANCE 100 Ohms
TIMER RANGE 500 ms to 500 s each side
LCD METER
TYPE
31/2 digits with Noiselok™
MAX. READING 2000 µA, 200 mV
POWER REQUIREMENTS 95-135 V or 220-240 V, 50/60 Hz
DIMENSIONS 17 x 8.75 x 9.5 in. (43 x 22 x 24 cm)
SHIPPING WEIGHT 21 lb (9.5 kg)

DVC-1000 Voltage Current Clamp
Includes two DVC3 preamps and one DVC2 dummy membrane.
Specify line voltage

OPTIONAL ACCESSORIES
DVC3 Replacement Preamplifier
2935 Rack Mount Kit
EK1 Ussing Electrode Kit (2 voltage, 2 current)
EKC Extra Ussing Current Electrode (red) (each)
EKV Extra Ussing Voltage Electrode (blue) (each)