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S-Nitroso-N-acetyl-D,L-penicillamine |
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SNAP is a stable green crystalline S-nitrosothiol compound that mimics the action of nitric oxide in vivo. It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors.
Contact us for details. sales@wpiinc.com |
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| M.W. 220.2 Purity > 98% by NMR or TLC | |||||||
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REFERENCES
Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1. Fehsel, K., et al. 1995. J. Immunol. 155, 2858. Gopalakrishna, R., et al. 1993. J. Biol. Chem. 268, 27180. Southam, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107. Henry, P.J., et al. 1989. J. Pharmacol. Exp. Therap. 248, 762. |
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It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors.