The ATP Sensor was developed along side a range of minimally invasive, needle-based electrochemical sensors for research and clinical diagnostic applications. This development programme is being carried out through the Department of Biological Sciences, University of Warwick, under the auspices 
of a grant award from the Wellcome Trust. The Company is focusing its attention on the purines, as indicators of neurological activity and disorders and has a product design platform that offers exquisite sensitivity, coupled with a broad linear activity range and high levels of accuracy and reproducibility.
Crucial to this highly differentiated technology is the process, whereby an active enzyme-based layer is deposited onto the surface of the sensor. In the case of the ATP sensor the enzyme matrix includes glycerol kinase and glycerol-3-phosphate oxidase, deposited onto the surface of a 2mm long Pt/Ir needle. The technology is underpinned by two patents (PCT/GB 03/01467 and PCT/GB2003/04984), which describe the sensor design concept and membrane coating respectively. Further IP is in the process of preparation. |