ATP Sensor

The ATP Sensor was developed along side a range of minimally invasive, needle-based electrochemical sensors for research and clinical diagnostic applications. This development programme is being carried out through the Department of Biological Sciences, University of Warwick, under the auspices Real Time Measurement of ATP
of a grant award from the Wellcome Trust. The Company is focusing its attention on the purines, as indicators of neurological activity and disorders and has a product design platform that offers exquisite sensitivity, coupled with a broad linear activity range and high levels of accuracy and reproducibility. Crucial to this highly differentiated technology is the process, whereby an active enzyme-based layer is deposited onto the surface of the sensor. In the case of the ATP sensor the enzyme matrix includes glycerol kinase and glycerol-3-phosphate oxidase, deposited onto the surface of a 2mm long Pt/Ir needle. The technology is underpinned by two patents (PCT/GB 03/01467 and PCT/GB2003/04984), which describe the sensor design concept and membrane coating respectively. Further IP is in the process of preparation.

Key Points
  • Suitable for in vitro and in vivo procedures
  • Minimally invasive
  • Reuseable (subject to calibration)
  • Contruct is enzyme-coated Pt wire
ATP Sensor Specifications
Shelf-life (dry) ≥ 4 months @ 4°C
Shelf-life (wet) ≤ 5 days
Sensor tip length 2 mm X 50 µm
Linear range 0.5 µM to 50 µM
Sensitivity 0.5 nA per µM
Fast response time (Typically 10-90% rise time = 10 secs)
WSA2001 ATP Starter Kit, includes sensors, reference and calibration materials
WSA1001 ATP Replacements Sensors (pk of 5)
503035 Reference Electrodes for ATP sensors
MICROC Potentiostat
MICROCP Replacement probe for Micro C