Dual Microiontophoresis Current Generator

Details

The Dual Microiontophoresis Current Generator is an electrically isolated, battery-operated instrument designed for the electro-iontophoresis of dyes, drugs and charged substances from micropipettes. Two identical battery operated current generators are available. In ordinary use, the two current generators are operated in parallel providing two distinct currents; one for preventing substances in the micropipette from outward diffusion (the retain or hold current) and the second for actively ejecting charged material. For pipettes with submicron tips, a hold current may not be necessary if there is little outward diffusion of pipette material. Model 260 is powered by two 9-volt alkaline batteries per side (four, in total); unique circuitry converts the ±9?V to ±100 V without a transformer, yielding an exceedingly quiet output.

for an excellent video introduction of the process, see the Jove Microiontophoresis and Micromanipulation for Intravital Fluorescence Imaging of the Microcirculation video.

 

OUTPUT	Constant current, floating
OUTPUT RANGES	0 to ±100 Na, 0 to ±1000 nA
OUTPUT POLARITY	Switch selected
COMPLIANCE (EXCURSION) VOLTAGE	100 V
METER	Analog meters, ±2% accuracy
OUTPUT RESISTANCE	>100 MMΩ
NOISE	Less than 20 μV typical DC to 10 kHz through 1 MMΩ independent of current delivery
LEAKAGE CURRENT TO GROUND	Less than 0.5 nA
OVERVOLTAGE ALARM	Front panel light
HOLD & EJECT SWITCH	Manual or by remote logic
POWER	Four 9 V alkaline batteries, included
DIMENSIONS	17 x 5.25 x 10 in.(43 x 13 x 25 cm)
SHIPPING WEIGHT	13 lb (5.9 kg)

260 Instruction Manual

P. Henny, B.E. Jones "Innervatio of orexin/hypocretin neurons by GABAergic, glutamatergic or cholinergic basal forebrain terminals evidenced by immunostaining for presynaptic vesicular transporter and postsynaptic scaffold" J of Comparative Neurology 499. 2006: 645-661

To place an order for this product, please contact the appropriate WPI office or distributor.

Customers from North America can order direct from our corporate office:
World Precision Instruments
175 Sarasota Center Boulevard
Sarasota, FL 34240-9258

• Phone or Fax
  Toll-free: 866-606-1974 Tel: 941-371-1003 Fax: 941-377-5428
Our Customer Service Representatives are available 8am - 6pm EST.
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International customers, please see our office and distributor contact information list.

There are no accessories for this product.

The image below shows a common application setup for the SYS-260. For a larger view, click on the image. WPI parts used include:

• 13620 Cable
• (2) 13776 2mm socket to banana adapter
• (2) 1986 banana shunts
• RC1T Ag/AgCl pellet to 2 mm pin
• MEH8-10 Glass holder Ag/AgCl to 2mm pin
• 2505 manipulator to electrode holder (use 5444 for Narishige or Zeiss manipulators)