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The SI-MB4 and SI-MB8 isolated tissue bath systems were developed for in vitro investigation on isolated smooth, cardiac or skeletal muscle preparations. They are specifically designed for pharmacological screening and testing that requires a high number of parallel samples. One advantage of this system is its modular structure, which allows the bath units to be used individually. The SIH vertical tissue bath systems offers easy control of the inflow and outflow of buffer, oxygenation and stimulation. Simple tissue installation, calibration of the chamber volume and temperature maintenance are also important features.
Features
- Modular system for testing tissue strips or rings
- Systems available with one to eight bath units
- 5, 10 and 20mL calibrated chamber volumes
- Oxygen delivery and control integrated into each chamber
- Field (or point) stimulation electrodes built into each tissue holder
- Automatic overflow
- Manual buffer replacement and draining
- Temperature control unit is external
- Water jacketed reservoirs with built-in oxygenators
- Easy operation
- Unique optical force transducers
Tissue Baths
Tissue baths come as small as 5mL, for your most delicate applications. All the SI-H tissue baths are precisely calibrated, so that when your tissue holder is installed, you can accurately calculate your solution concentration.
Oxygenation
SI-H re-engineered the standard oxygen frit to avoid the disturbances to the tissue sample that tiny bubbles can cause. The repositionable SI-H frit is installed on a small wire attached to the tissue mounts. You can choose the depth and direction of the bubble stream that will cause the least disruption to your tissue. Because the frit is a removable part, it can be easily replaced without the need to order a new tissue bath.
Tissue Holders
All tissue holders are made of Teflon to prevent the contamination of the tissue buffer by trace metals. The tissue holders are designed to:
- Permit the proper installation of the tissue on the holder before it is positioned in the chamber.
- Effectively oxygenate the buffer in the vicinity of the tissue.
- Position the field (or point) electrodes for efficient stimulation.
- Permit easy calibration of the chamber volume.
Three tissue holder styles are available for testing tissue.
- SI-OHO2F–tissue strips with field stimulation, also used for vascular rings
- SI-OHO2P–tissue strips with point stimulation
System Specifications
| |
SI-MB4 |
SI-MB8
|
Width
|
500mm
|
500mm |
Length
|
1000mm
|
2000mm
|
Height
|
1050mm
|
1050mm
|
| Weight |
30kg |
60kg |
Tissue Bath Specifications
| |
Height* |
ID
|
5mL
|
65mm
|
14mm
|
| 10mL |
65mm
|
18mm
|
| 20mL |
65mm
|
20mm
|
* Inside height is measured between the outflow port at the bottom and the overflow port at the top.
This system includes:
2 Base plates and frames
8 tissue chamber holders
8 buffer reservoirs
8 single plane manipulators
8 glass tissue chambers (Select size)
8 tissue holders (Select type)
16 vascular ring hooks
8 SI-KG20 force transducers
2 4-Channel bridge amplifiers (SI-BAM21LCB) and amplifier frame (SI-BFMA)
Suture (4-0 Silk, 18" and 6-0 Silk, 18")
To place an order for this product, please contact the appropriate WPI office or distributor.
Customers from North America can order direct from our corporate office:
World Precision Instruments
175 Sarasota Center Boulevard
Sarasota, FL 34240-9258
- Phone or Fax
Toll-free: 866-606-1974 Tel: 941-371-1003 Fax: 941-377-5428
Our Customer Service Representatives are available 8am - 6pm EST.
- Online Store
Many of our products are available for purchase through our online store.
At this time we can only accept orders from the U.S. through the online store.
-
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International customers, please see our
office and distributor contact information list.
