Get More Insight from Every Measurement
Go beyond traditional TEER with EVOM™ Auto ElectroZ, combining trusted barrier resistance measurements with advanced electrochemical impedance spectroscopy (EIS) on a single automated, high-throughput platform.
With interchangeable electrode arrays, switch between Classic mode for traditional TEER measurements and ElectroZ mode for multifrequency EIS analysis. ElectroZ reveals additional insights into cellular barrier integrity, morphology, maturation, and polarization, helping you understand not just whether a barrier is intact, but how cells develop and respond to experimental conditions.
ElectroZ automatically calculates five key parameters:
- TEER Cellular: Determines cell layer resistance without requiring a separate blank measurement or manual background subtraction.
- TEER Total: Measures the combined resistance of the cell layer and surrounding solution.
- Transepithelial Capacitance (TEC): Provides insights into cellular growth, morphology, and maturation.
- Tau Ratio or Membrane Ratio: Indicates cellular polarization through the relationship between apical and basolateral membrane properties.
- Goodness of Fit: Evaluates how closely the measured impedance data fits the equivalent cell circuit model.
Together, these measurements provide a more complete picture of cellular barrier development and function.
Explore ElectroZ: Advanced Insights for Barrier Research
From routine barrier assessment to complex cellular models, ElectroZ provides additional insights into living cell behavior throughout an experiment.
- Barrier Integrity: Evaluate epithelial and endothelial barrier resistance and tight junction maturation.
- Cell Growth and Development: Track changes in cell attachment, proliferation, morphology, and barrier maturation.
- Cell Morphology and Function: Investigate changes in membrane properties and cellular polarization.
- Drug and Toxicology Research: Monitor cellular responses to drugs, toxins, and environmental conditions.
- Culture Quality Control: Establish measurement thresholds to identify samples that meet experimental criteria.
- Complex Culture Models: Study polarized epithelial cultures, gastrointestinal and blood-brain barrier models, co-cultures, and engineered tissues.
Advanced Analysis. Simplified Workflow.
EVOM™ Auto ElectroZ combines sophisticated EIS analysis with the convenience of automated, high-throughput measurement.
- Automated Measurements: Analyze compatible 24- and 96-well plates with minimal hands-on operation.
- Scheduled Operation: Program repeated measurements at defined intervals to monitor cellular changes throughout an experiment.
- Flexible EIS Analysis: Use WPI-optimized frequency settings, create custom profiles, or take advantage of the frequency optimizer.
- Powerful Data Visualization: Access Nyquist and Bode plots, equivalent circuit fitting results, and raw impedance data for further analysis.
- Integrated Quality Control: Flag measurements using user-defined thresholds, automate electrode rinsing, and reduce opportunities for sample cross-contamination.
From routine TEER screening to advanced cellular characterization, ElectroZ makes complex measurements easier to perform and interpret.
Ready to Go Beyond TEER?
Discover how EVOM™ Auto ElectroZ can expand your barrier research with advanced EIS analysis, automated workflows, and greater experimental flexibility. Complete the form to connect with a WPI specialist and explore the capabilities of ElectroZ for your research.